{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:07:43Z","timestamp":1747188463281,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009122","name":"Ministry of Higher Education and Scientific Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009122","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To present the clinical signs and treatment methods for atypical tumor\u2010like meibomitis in two dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals Studied<\/jats:title><jats:p>A 4\u2010year\u2010old castrated\u2010male Coton de Tulear (Case 1) and a 6\u2010year\u2010old spayed\u2010female Maltese dog (Case 2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>Full ophthalmic examination revealed a well\u2010circumscribed, firm, and raised solitary mass on the upper eyelid of the left (Case 1) and right eye (Case 2). Case 1 showed a recurrent mass with a diameter of 2\u20133\u2009mm, which was excised by the referring veterinarian. The possibility of meibomian gland involvement was suggested histopathologically. Case 2 had a history of blepharitis treated with systemic corticosteroids 4\u2009years ago.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Topical and systemic antibiotics and anti\u2010inflammatory drugs were administered to reduce inflammation and prevent secondary infections. In Case 1, the mass appeared static at the beginning of medication; however, after stopping antibiotics while tapering steroids, the mass increased in size and was associated with suppurative discharge. In Case 2, the mass continued to grow despite treatment, showing a similar infection pattern. Cytological examination revealed neutrophilic inflammation with cocci infection, and bacterial culture confirmed the presence of <jats:italic>Staphylococcus pseudintermedius<\/jats:italic> in both cases. When steroid administration was stopped and antibiotic administration was initiated according to the results of the antibiotic susceptibility test, the mass rapidly decreased in size and completely disappeared. There was no recurrence on follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A unilateral antibiotic\u2010responsive tumor\u2010like solitary mass on the upper eyelid resolved without surgical treatment. Medical treatment must be considered when treating atypical eyelid masses, and the use of appropriate antibiotics through antibiotic susceptibility testing is important.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.13046","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T14:38:21Z","timestamp":1671547101000},"page":"458-463","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Atypical antibiotic\u2010responsive <i>Staphylococcus pseudintermedius<\/i>\u2010associated tumor\u2010like meibomitis in the upper eyelid: A case report of two dogs"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2309-4620","authenticated-orcid":false,"given":"Sol","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Veterinary Ophthalmology College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University  Seoul 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