{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:20:09Z","timestamp":1765484409413,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T00:00:00Z","timestamp":1712707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the clinical outcomes of chemical ciliary body ablation (CBA) in dogs with chronic glaucoma and concurrent anterior lens luxation and to investigate adverse ocular effects of this procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>Retrospective review of 17 dogs (18 eyes) with chronic glaucoma and concurrent anterior lens luxation treated with intravitreal gentamicin with or without dexamethasone sodium phosphate or triamcinolone acetonide. Data collected included signalment, concurrent ocular disease, topical medications prescribed, follow\u2010up duration, and intraocular pressure (IOP) pretreatment, posttreatment, and at the last follow\u2010up visit. Success was defined as an IOP &lt;25\u2009mmHg with no additional procedures or ocular hypotensive medications at the last examination to date.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The success rate for CBA in dogs with chronic glaucoma and concurrent anterior lens luxation was 88.9% without the need of additional surgical or ocular hypotensive therapies. Glaucoma was suspected to be secondary to lens luxation in 72.2% of cases. The most common postoperative complications were phthisis bulbi (50.0%), keratoconjunctivitis sicca (27.8%), and uveitis (27.8%). Long\u2010term management with topical nonsteroidal anti\u2010inflammatories, corticosteroids, and\/or immunomodulators was needed in 70.6% of cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CBA with intravitreal injection of gentamicin is effective at maintaining an IOP &lt;25\u2009mmHg in dogs with chronic glaucoma and concurrent anterior lens luxation. Management of postoperative sequelae commonly requires continued use of topical medications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.13217","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T09:55:25Z","timestamp":1712742925000},"page":"315-322","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Chemical ciliary body ablation in dogs with chronic glaucoma and anterior lens luxation: A retrospective review from 2017 to 2022"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1920-528X","authenticated-orcid":false,"given":"Cristina","family":"King","sequence":"first","affiliation":[{"name":"BluePearl Veterinary Partners  Clearwater Florida USA"},{"name":"BluePearl Veterinary Partners  Sarasota Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica M.","family":"Stine","sequence":"additional","affiliation":[{"name":"BluePearl Veterinary Partners  Clearwater Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Welihozkiy","sequence":"additional","affiliation":[{"name":"BluePearl Veterinary Partners  Sarasota Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terri L.","family":"Baldwin","sequence":"additional","affiliation":[{"name":"BluePearl Veterinary Partners  Clearwater Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2001.tb00084.x"},{"key":"e_1_2_11_3_1","first-page":"1173","volume-title":"Veterinary Ophthalmology","author":"Plummer CE","year":"2021"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2015.06.009"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2012.01019.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12071"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2015.06.008"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.69.847"},{"issue":"14","key":"e_1_2_11_9_1","first-page":"134","article-title":"Intraocular gentamicin for the control of endophthalmitis and glaucoma in animals","volume":"14","author":"Vainisi SJ","year":"1983","journal-title":"Am Coll Vet Ophthalmol"},{"key":"e_1_2_11_10_1","first-page":"113","article-title":"Intraocular gentamicin and glaucoma: a retrospective study of 60 dog and cat eyes (1985\u20131993)","volume":"4","author":"Bingaman D","year":"1995","journal-title":"Vet Comp Ophthalmol"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.17555\/jvc.2017.10.34.5.341"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12258"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12816"},{"issue":"6","key":"e_1_2_11_14_1","first-page":"406","article-title":"Effectiveness of gentamicin for pharmacologic ablation to treat end stage glaucoma in dogs [abstract]","volume":"14","author":"Marchione BA","year":"2011","journal-title":"Vet Ophthalmol"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2012.01050.x"},{"key":"e_1_2_11_16_1","unstructured":"Icare TONOVET Tonometer TV01 Manual.2014https:\/\/tonovet.com\/products\/icare\u2010vet\/vet\u2010brochure\/"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.5455\/OVJ.2022.v12.i6.6"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2004.04006.x"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12066"},{"key":"e_1_2_11_20_1","first-page":"280","volume-title":"Surgical Procedures for the Glaucomas. 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