{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T07:23:11Z","timestamp":1787383391891,"version":"build-2736575974"},"reference-count":64,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine the efficacy of freeze\u2010dried amniotic membrane (FDAM) used in veterinary medicine (Vetrix EyeQ) for the surgical treatment of deep melting ulcers in dogs and cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A total of 15 dogs and 5 cats treated for deep melting corneal ulcers were included in this retrospective study. Following keratectomy, a simple or multilayer FDAM was placed into the keratectomy bed and sutured with 9\/0 polyglactin suture material. A temporary third eyelid flap was performed for each case. Follow\u2010up examinations were performed on average 18, 45, and 90\u2009days after surgery. Final evaluation included assessment of corneal healing, preserved vision, and residual corneal opacities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 20 eyes were treated between 2019 and 2023. Nine dog and four cat breeds were represented. Mean healing time was 17\u2009\u00b1\u20092\u2009days. At 18\u2009days postsurgery, inflammatory reaction with superficial vascularization was present in all eyes (20\/20). At 45\u2009days, 45% (9\/20) of eyes showed persistent corneal neovascularization, mild corneal fibrosis, and focal corneal pigmentation. At 90\u2009days, persistent severe pigmentation was observed in 10% (2\/20) of eyes. Corneal transparency was successfully restored, and vision was preserved in 90% of cases (18\/20).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>FDAM transplantation was effective in treating melting corneal ulcers in dogs and cats.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.70023","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T06:38:59Z","timestamp":1746427139000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Surgical Repair of Deep Melting Ulcers With Freeze\u2010Dried Amniotic Membrane Transplantation in Dogs and Cats"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5009-6665","authenticated-orcid":false,"given":"Clo\u00e9","family":"Lengell\u00e9","sequence":"first","affiliation":[{"name":"Centre V\u00e9t\u00e9rinaire Vetes  Walhain Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12885"},{"key":"e_1_2_8_3_1","first-page":"1122","volume-title":"Veterinary Ophthalmology","author":"Whitley D. 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