{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:05:19Z","timestamp":1792692319571,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T00:00:00Z","timestamp":1753574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T00:00:00Z","timestamp":1753574400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Corneal sequestrum is a condition commonly observed in cats, though the pathogenesis is not fully understood. The occurrence of conjunctival sequestrum has not previously been documented. This report aims to describe a series of cases of conjunctival sequestra in cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals and Animal Samples Studied<\/jats:title>\n                    <jats:p>A 3\u2010year\u2010old male Persian cat presented after 2\u2009months of blepharospasm and epiphora in the right eye, accompanied by mild conjunctival hyperemia. Histopathologic findings from four other cases are also included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>After presentation of Patient 1, the database (from 2007 to 2025) of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) was searched for other cases of feline conjunctival sequestrum, four of which were identified. In all cases, an amorphous black plaque was observed in the conjunctival tissue during the ophthalmological examination. Three of the four cases also had corneal sequestra ipsilaterally. Histopathology of the corneal sequestra was available in two of the cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Histopathology of all five conjunctival lesions revealed focally extensive compaction and brunescence of proprial collagen and absence of fibroblasts. Three of the cases had conjunctival ulceration overlying the sequestrum. The surrounding substantia propria was variably infiltrated by inflammatory cells and microorganisms. The appearance of conjunctival sequestra was remarkably similar to that of corneal sequestra.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Clinical Relevance<\/jats:title>\n                    <jats:p>This is the first reported case\u2010series of feline conjunctival sequestrum. Variable presentation of concurrent ocular abnormalities and history led to no definitive conclusion to a common cause. Similar to corneal sequestra, chronic irritation and a possible contribution from FHV\u20101 infection are suspected.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.70056","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T04:29:47Z","timestamp":1753676987000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Feline Conjunctival Sequestra\u2014A Case Series"],"prefix":"10.1111","volume":"29","author":[{"given":"Carolina Cauduro","family":"da Rosa","sequence":"first","affiliation":[{"name":"Comparative Ophthalmology Laboratory Federal University of Paran\u00e1, UFPR  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett D.","family":"Story","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine University of California\u2013Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangwan","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences, School of Veterinary Medicine University of California\u2013Davis  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian C.","family":"Shaw","sequence":"additional","affiliation":[{"name":"Comparative Ocular Pathology Laboratory of Wisconsin, School of Veterinary Medicine University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro B. C.","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Comparative Ocular Pathology Laboratory of Wisconsin, School of Veterinary Medicine University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1375-0643","authenticated-orcid":false,"given":"Jacob","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bret A.","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3933-8864","authenticated-orcid":false,"given":"Fabiano","family":"Montiani\u2010Ferreira","sequence":"additional","affiliation":[{"name":"Comparative Ophthalmology Laboratory Federal University of Paran\u00e1, UFPR  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,27]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"24","article-title":"Feline Corneal Sequestration: A Retrospective Study of 42 Cases (1987\u20131991)","volume":"30","author":"Morgan R. 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