{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T05:30:22Z","timestamp":1774848622999,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To characterize the conjunctival bacterial flora of laboratory\u2010housed New Zealand White (NZW) rabbits using conventional culture techniques and quantitative bacterial analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals Studied<\/jats:title>\n                    <jats:p>This experimental study involved the collection of conjunctival fornix samples from 24 eyes of 12 healthy laboratory\u2010housed NZW rabbits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedures<\/jats:title>\n                    <jats:p>Conjunctival samples were obtained using sterile dry swabs and processed using standard microbiological techniques. Bacterial identification was performed via mass spectrometry (MALDI\u2010TOF), and quantification was expressed in colony\u2010forming units per milliliter (CFU\/mL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Bacterial growth was observed in 74% of the samples (17\/24 eyes), with seven species identified:\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Moraxella cuniculi<\/jats:italic>\n                      <\/jats:styled-content>\n                      ,\n                      <jats:italic>Corynebacterium<\/jats:italic>\n                      spp., coagulase\u2010negative\n                      <jats:italic>Staphylococcus<\/jats:italic>\n                      ,\n                      <jats:italic>Bacillus<\/jats:italic>\n                      spp.,\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      <\/jats:styled-content>\n                      ,\n                      <jats:italic>Streptococcus viridans<\/jats:italic>\n                      group, and\n                      <jats:italic>Tsukamurella<\/jats:italic>\n                      spp. Although most isolates were Gram\u2010positive,\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>M. cuniculi<\/jats:italic>\n                      <\/jats:styled-content>\n                      \u2014a Gram\u2010negative bacterium\u2014was the predominant species. It exhibited the highest bacterial load (CFU\/mL) and demonstrated a statistically significant difference compared to the other species (Kruskal\u2013Wallis,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01).\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>M. cuniculi<\/jats:italic>\n                      <\/jats:styled-content>\n                      also exhibited the highest variability in CFU\/mL values among all isolates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Despite the predominance of Gram\u2010positive isolates,\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>M. cuniculi<\/jats:italic>\n                      <\/jats:styled-content>\n                      was identified as the predominant species in the conjunctival flora of healthy NZW rabbits, both in frequency and bacterial load. These findings contribute to a more detailed characterization of the ocular microbiota in this commonly used laboratory model.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.70073","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T03:54:29Z","timestamp":1756526069000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Characterization of Conjunctival Bacterial Flora of Healthy Laboratory\u2010Housed New Zealand White Rabbits"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1179-5542","authenticated-orcid":false,"given":"Denisse","family":"Espinosa\u2010Encalada","sequence":"first","affiliation":[{"name":"Ophthalmology Department Virgen de la Luz Hospital  Cuenca Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4475-9492","authenticated-orcid":false,"given":"Raquel","family":"Maroto Cejudo","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Virgen de la Luz Hospital  Cuenca Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d3scar","family":"Esparcia Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Microbiology Department University Hospital Complex of Albacete (CHUA)  Albacete Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f3nica","family":"G\u00f3mez Juarez Sango","sequence":"additional","affiliation":[{"name":"Animal Experimentation Unit University Hospital Complex of Albacete (CHUA)  Albacete Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Andr\u00e9s Pretel","sequence":"additional","affiliation":[{"name":"Clinical Research Support Unit (UdAIC) University Hospital Complex of Albacete (CHUA)  Albacete Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Cava Valenciano","sequence":"additional","affiliation":[{"name":"Ophthalmology Department University Hospital Complex of Albacete (CHUA)  Albacete Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8071033"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2020.1788100"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12989"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12743"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748\u20105827.1976.tb06947.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12925"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.1994.55.07.949"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1972.161.02.201"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2005.04061.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1016011105560"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2008.00620.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2009.00728.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.7589\/0090\u20103558\u201038.4.851"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmp.12059"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms6030068"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ahe.12284"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ame2.12218"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104\u2010015\u20100995\u20101"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.149.8.232"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.26873\/SVR-24724-2016"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.5812\/jjm.9678"},{"issue":"6","key":"e_1_2_10_23_1","first-page":"656","article-title":"Microbiologic, Radiographic, and Anatomic Study of the Nasolacrimal Duct Apparatus in the Rabbit (Oryctolagus Cuniculus)","volume":"46","author":"Marini R. 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