{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T05:32:40Z","timestamp":1774848760633,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To establish the central corneal thickness (CCT) and intraocular pressure (IOP) of normal Holstein cattle and any relationship with age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Age of 50 Holstein cattle was recorded in days. CCT was measured by ultrasonic pachymetry, and IOP values were recorded by rebound tonometry from a total of 100 eyes. CCT and IOP values were subsequently analyzed in relation to age. The animals were divided into the following two groups: calves (&lt; 360\u2009days old) and adults (\u2265 360\u2009days old).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean CCT value of all animals was 723.1\u2009\u00b1\u200975.9\u2009\u03bcm in the right eye, 714.5\u2009\u00b1\u200982.2\u2009\u03bcm in the left eye. Mean IOP value of 100 eyes was 25.4\u2009\u00b1\u20098.07\u2009mm\/Hg in the right eye, 24\u2009\u00b1\u20097.89\u2009mm\/Hg in the left eye. Mean CCT and IOP values of the animals &lt; 360\u2009days old were 697.7\u2009\u00b1\u20098.28\u2009\u03bcm and 21.6\u2009\u00b1\u20090.77\u2009mm\/Hg respectively. Mean CCT and IOP values of the animals \u2265 360\u2009days old were 768.1\u2009\u00b1\u200914.4\u2009\u03bcm and 31.9\u2009\u00b1\u20091.18\u2009mm\/Hg, respectively. A statistically significant difference was observed between the groups in terms of CCT and IOP values (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). A positive correlation was identified between CCT and age (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.57,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and between IOP and age (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.488,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study documents the age\u2010related increase in both CCT and IOP values in cattle.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.70082","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T03:29:57Z","timestamp":1758598197000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Central Corneal Thickness and Intraocular Pressure Increases With Age in Normal Holstein Cattle"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1490-8832","authenticated-orcid":false,"given":"B\u00fc\u015fra","family":"Kibar Kurt","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine, Surgery Department University of Aydin Adnan Menderes  T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3335-7247","authenticated-orcid":false,"given":"Erman","family":"G\u00fclenda\u011f","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine, Department of Biostatistics University of Siirt  T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvfa.2014.11.006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvfa.2010.09.003"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.5171\/2015.709104"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2010.00806.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2019.05.008"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvfa.2010.08.003"},{"key":"e_1_2_10_8_1","first-page":"18","article-title":"Clinical and Pathological Study of a Cow With Chronic Glaucoma","volume":"6","author":"Mertel L.","year":"1996","journal-title":"Progress in Veterinary and Comparative Ophthalmology"},{"key":"e_1_2_10_9_1","first-page":"98","article-title":"Incidence of Eye Diseases of Bovine in Assam","volume":"14","author":"Sarma B.","year":"1990","journal-title":"Indian Veterinary Journal"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvfa.2010.08.005"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08\u20102410"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463\u20105224.1998.00017.x"},{"issue":"4","key":"e_1_2_10_13_1","first-page":"195","article-title":"Central Corneal Thickness Increases With Age in Cattle","volume":"27","author":"Kurt K. 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