{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T05:22:52Z","timestamp":1774848172255,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n \n To describe a subconjunctival granuloma caused by\n Dirofilaria repens<\/jats:italic>\n in a dog from Rayong province, eastern Thailand, along with the successful treatment outcomes. The causative nematode was identified through morphological examination and molecular techniques.\n <\/jats:p>\n <\/jats:sec>\n \n Animal Studied<\/jats:title>\n A 5\u2010year\u2010old female mixed\u2010breed dog was presented with a subconjunctival mass at the temporal part of the left bulbar conjunctiva. The dog lived indoors with its owner.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A complete ophthalmic examination was performed. The mass was surgically removed and submitted for histopathological examination. During the surgery, a long, slender, white\u2010creamy nematode emerged from the mass, which was sent for parasitology examination and molecular identification. The left eyelids were closed using temporary tarsorrhaphy. Selamectin spot\u2010on and doxycycline were prescribed.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Two weeks after surgery, the temporary tarsorrhaphy was removed. The excision site had healed completely without recurrence. The histopathological examination revealed eosinophilic granulomatous inflammation. A parasitic nematode was identified in the genus\n Dirofilaria<\/jats:italic>\n spp. The full\u2010length mitochondrial genome analysis showed 99.8% coverage of\n Dirofilaria repens<\/jats:italic>\n sequences.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n \n D. repens<\/jats:italic>\n <\/jats:styled-content>\n infection caused a subconjunctival granuloma in the current case. The treatments, combined with surgical excision and selamectin spot\u2010on, resulted in a good response. The conjunctival wound had healed completely within 2\u2009weeks, without complications or recurrences. To the authors' knowledge, this was the first report of canine subconjunctival dirofilariasis caused by\n \n D. repens<\/jats:italic>\n <\/jats:styled-content>\n in Thailand. The vector\u2010borne transmission of\n \n D. repens<\/jats:italic>\n <\/jats:styled-content>\n , a zoonotic nematode, via mosquito bites in humans, should be a concern in Thailand, particularly in the eastern region.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/vop.70094","type":"journal-article","created":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T07:35:01Z","timestamp":1759131301000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Subconjunctival Granuloma Caused by\n \n Dirofilaria repens<\/i>\n <\/scp>\n in an Indoor Dog From Thailand: A Case Report and Mitochondrial Genome Analysis"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5179-1653","authenticated-orcid":false,"given":"Natthanet","family":"Sritrakoon","sequence":"first","affiliation":[{"name":"Ophthalmology Unit Kasetsart University Veterinary Teaching Hospital, Faculty of Veterinary Medicine Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pongpun","family":"Sawatwong","sequence":"additional","affiliation":[{"name":"Thailand Ministry of Public Health (MOPH) U.S. Centers for Disease Control and Prevention Collaboration (TUC) Nonthaburi Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kannika","family":"Siripattarapravat","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Veterinary Medicine Kasetsart University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duangkamon","family":"Siludjai","sequence":"additional","affiliation":[{"name":"Thailand Ministry of Public Health (MOPH) U.S. Centers for Disease Control and Prevention Collaboration (TUC) Nonthaburi Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Famui","family":"Mueanpai","sequence":"additional","affiliation":[{"name":"Thailand Ministry of Public Health (MOPH) U.S. Centers for Disease Control and Prevention Collaboration (TUC) Nonthaburi Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peera","family":"Hemarajata","sequence":"additional","affiliation":[{"name":"Association of Public Health Laboratories Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sutawee","family":"Suksin","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit Kasetsart University Veterinary Teaching Hospital, Faculty of Veterinary Medicine Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wissanuwat","family":"Chimnoi","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Veterinary Medicine Kasetsart University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nutsuda","family":"Klinkaew","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Veterinary Medicine Kasetsart University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burin","family":"Nimsuphan","sequence":"additional","affiliation":[{"name":"Ophthalmology Unit Kasetsart University Veterinary Teaching Hospital, Faculty of Veterinary Medicine Bangkok Thailand"},{"name":"Department of Parasitology, Faculty of Veterinary Medicine Kasetsart University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2012.50.2.137"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010017\u20102434\u20108"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11686\u2010022\u201000543\u20103"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2021.2851\u20102854"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1983.32.1456"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/tp.TP_113_20"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249\u2010025\u201001328\u20102"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12795"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajoc.2022.101570"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.15413\/ajsr.2017.0179"},{"key":"e_1_2_8_12_1","first-page":"79","volume-title":"Slatter's Fundamentals of Veterinary Ophthalmology","author":"Maggs D. 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