{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T05:27:05Z","timestamp":1774848425230,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 15\u2010week\u2010old Australian Labradoodle puppy was presented to The University of Queensland Small Animal Hospital for bilateral eyelid agenesis\/coloboma and associated ocular complications. Enucleation of the left globe and repair of the right eyelid via a lip\u2010to\u2010lid transmucosal flap was performed. Given the subsequent development of prolapse of the gland of the nictitating membrane and a lack of vision of the right eye, enucleation of the right globe was then performed 2\u2009months following the initial procedure. Both globes and a skin wedge from the right eye were submitted to The University of Queensland Veterinary Laboratory Service for histopathology assessment. Microscopic globe examination revealed lesions consistent with bilateral Peters' anomaly (anterior chamber cleavage syndrome, ACCS), characterized by axial defects in Descemet's membrane and the posterior corneal stroma, anterior synechiae at the site of the defects, and closure of the drainage angle. Other important histological findings were persistent pupillary membranes, retinal separation, and aphakia. Histopathology of the skin wedge from the right eye demonstrated complete absence of conjunctival goblet cells, tarsal plate, and meibomian glands, consistent with the finding of eyelid agenesis\/coloboma. This report describes an uncommon and underreported presentation of bilateral canine lower eyelid agenesis with concurrent multiple congenital ocular anomalies, including bilateral Peters' anomaly.<\/jats:p>","DOI":"10.1111\/vop.70164","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T12:05:21Z","timestamp":1772971521000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral Eyelid Agenesis With Multiple Congenital Ocular Anomalies in an Australian Labradoodle Puppy: Case Report and Surgical Management"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4279-2948","authenticated-orcid":false,"given":"Chi Hin","family":"Ng","sequence":"first","affiliation":[{"name":"School of Veterinary Science, Gatton Campus The University of Queensland  Gatton Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4148-4315","authenticated-orcid":false,"given":"Ticiana Brasil","family":"Ervedosa","sequence":"additional","affiliation":[{"name":"School of Veterinary Science, Gatton Campus The University of Queensland  Gatton Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6860-0166","authenticated-orcid":false,"given":"Jos\u00e9 Granados","family":"Soler","sequence":"additional","affiliation":[{"name":"School of Veterinary Science, Gatton Campus The University of Queensland  Gatton Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5278-6725","authenticated-orcid":false,"given":"Megan Elizabeth","family":"Climans","sequence":"additional","affiliation":[{"name":"Comparative Ocular Pathology Laboratory of Wisconsin, Department of Pathobiological Sciences School of Veterinary Medicine, University of Wisconsin  Madison Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4208-361X","authenticated-orcid":false,"given":"Viviana","family":"Gonzalez\u2010Astudillo","sequence":"additional","affiliation":[{"name":"School of Veterinary Science, Gatton Campus The University of Queensland  Gatton Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"issue":"1","key":"e_1_2_9_2_1","first-page":"105","article-title":"Congenital and Acquired Ocular Abnormalities in a Dog: Clinical Description and Management","volume":"74","author":"Uygur A.","year":"2025","journal-title":"Veterin\u00e1ria"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12836"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/13816810.2015.1071409"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2002.00219.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/vetreccr-2016-000301"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2002.00237.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.23.04.0203"},{"key":"e_1_2_9_9_1","first-page":"35","article-title":"An Update on Ocular Colobomata in Snow Leopards (Uncia uncia)","volume":"10","author":"Lengger J.","year":"2013","journal-title":"International Pedigree Book of Snow Leopards"},{"key":"e_1_2_9_10_1","first-page":"39","article-title":"Feline Colobomatous Syndrome","volume":"7","author":"Martin C. 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