{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:11:10Z","timestamp":1778659870378,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To report retinal optical coherence tomography (OCT) findings in a dog with chronic uveodermatologic syndrome (UDS) and to correlate these findings with clinical features to aid in diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animal Studied<\/jats:title>\n                    <jats:p>A 7\u2010year\u2010old spayed female mixed\u2010breed dog presented with red eyes and suspected vision loss. She had a history of panuveitis and bilateral bullous retinal detachments diagnosed 3\u2009years earlier.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Complete ophthalmic examination was performed to evaluate active anterior uveitis and inactive chorioretinitis. Physical exam revealed new vitiligo and skin biopsies of the nasal planum and eyelids confirmed a diagnosis of UDS by a dermatopathologist. Fundus photography documented the retinal lesions and OCT characterized the changes to retinal structure. GLS\u20101027, a novel anti\u2010inflammatory medication, was started after the most recent flare up in an attempt to control future flare ups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>RetCam fundus photography revealed well\u2010demarcated areas of tapetal hyperreflectivity, hyperpigmented scarring, and non\u2010tapetal depigmentation. OCT b\u2010scans revealed normal retinal layering in unaffected areas and marked pathologic changes in affected areas. These changes included diffuse structural alteration of the retina in areas of hyperpigmented scarring and hypopigmented regions with partial\u2010to\u2010complete loss of retinal thickness and structure. 12\u2009months after the last recheck, the dog continued to receive oral GLS\u20101027 and had no recurrence of clinical signs on ocular exam.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study represented the first documentation of in\u00a0vivo retinal changes in UDS using OCT imaging. This case highlighted the potential of OCT to visualize retinal changes in UDS and suggests its possible utility in disease monitoring.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.70183","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:11:17Z","timestamp":1777644677000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Features of Optical Coherence Tomography (\n                    <scp>OCT<\/scp>\n                    ) in a Case of Chronic Uveodermatologic Syndrome"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1858-1491","authenticated-orcid":false,"given":"Alexa P.","family":"Gray","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine, Cornell University  Ithaca New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1894-8839","authenticated-orcid":false,"given":"Eric C.","family":"Ledbetter","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine, Cornell University  Ithaca New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9610-9040","authenticated-orcid":false,"given":"Jeanine","family":"Peters\u2010Kennedy","sequence":"additional","affiliation":[{"name":"Department of Population Medicine and Diagnostic Sciences College of Veterinary Medicine, Cornell University  Ithaca New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Population Medicine and Diagnostic Sciences College of Veterinary Medicine, Cornell University  Ithaca New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9702-7298","authenticated-orcid":false,"given":"Erin M.","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine, Cornell University  Ithaca New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-019-2003-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.252.10.1263"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2005.00508.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.17221\/10\/2025-VETMED"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.165.12.7323"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2016.02.002"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-016-0412-4"},{"key":"e_1_2_9_9_1","volume-title":"StatPearls","author":"Stern E. 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