{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:22:24Z","timestamp":1783441344319,"version":"3.54.6"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study aimed to evaluate the feasibility of visualizing and quantitatively analyzing the corneal endothelium of sheep using a specular microscope designed for a human eye bank. Twenty\u2010four healthy corneas from 12 one\u2010year\u2010old male sheep (\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Ovis aries<\/jats:italic>\n                    <\/jats:styled-content>\n                    ) were examined. Four central endothelial images per cornea were analyzed using a semi\u2010automated method. Endothelial parameters were automatically calculated by the proprietary software integrated into the specular microscope, including endothelial cell density (ECD), average cell area (AVE), coefficient of variation (CV) in cell size, and percentage of hexagonal cells (HEX). Data normality was assessed using the Kolmogorov\u2013Smirnov test, and paired comparisons between right and left eyes were performed using Student's\n                    <jats:italic>t<\/jats:italic>\n                    \u2010test. High\u2010quality endothelial images were successfully obtained from all corneas. The mean ECD was 3198.3\u2009\u00b1\u2009428.3 cells\/mm\n                    <jats:sup>2<\/jats:sup>\n                    , AVE was 318.7\u2009\u00b1\u200942.3\u2009\u03bcm\n                    <jats:sup>2<\/jats:sup>\n                    , CV in cell size was 38.0%\u2009\u00b1\u20097.9%, and HEX was 57.7%. No statistically significant differences were observed between right and left eyes for any parameter (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.05). A human eye bank specular microscope allows reliable visualization and quantitative assessment of the ovine corneal endothelium, demonstrating its applicability in experimental and translational veterinary ophthalmology.\n                  <\/jats:p>","DOI":"10.1111\/vop.70190","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:47:04Z","timestamp":1779252424000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the Ovine Corneal Endothelium Using a Human Eye Bank Specular Microscope"],"prefix":"10.1111","volume":"29","author":[{"given":"Tanise Carboni","family":"da Silva","sequence":"first","affiliation":[{"name":"Veterinary College Federal University of Rio Grande do Sul, UFRGS  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"da Fonseca Lopes Pinto","sequence":"additional","affiliation":[{"name":"Veterinary College Federal University of Rio Grande do Sul, UFRGS  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alana Pinto","family":"de Melo","sequence":"additional","affiliation":[{"name":"Veterinary College Federal University of Rio Grande do Sul, UFRGS  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelle","family":"Bettio","sequence":"additional","affiliation":[{"name":"Veterinary College Federal University of Rio Grande do Sul, UFRGS  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0050-5039","authenticated-orcid":false,"given":"Diane Ruschel","family":"Marinho","sequence":"additional","affiliation":[{"name":"Hospital de Cl\u00ednicas de Porto Alegre (HCPA)  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Silva","family":"Guareze","sequence":"additional","affiliation":[{"name":"Hospital de Cl\u00ednicas de Porto Alegre (HCPA)  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1541-9133","authenticated-orcid":false,"given":"Jo\u00e3o Antonio Tadeu","family":"Pigatto","sequence":"additional","affiliation":[{"name":"Veterinary College Federal University of Rio Grande do Sul, UFRGS  Porto Alegre RS Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1990.53"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181cc7961"},{"key":"e_1_2_12_4_1","volume-title":"Cornea","author":"Krachmer J. 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