{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:24:22Z","timestamp":1783441462898,"version":"3.54.6"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate treatment outcomes in cats with eosinophilic keratitis (EK).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals Studied<\/jats:title>\n                    <jats:p>Twenty\u2010eight cats (32 eyes), median age 7.9\u2009years (range 1.2\u201318.0), diagnosed with EK.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedures<\/jats:title>\n                    <jats:p>Medical records of cats diagnosed with EK from 2014 to 2022 were included if clinical signs or cytology were consistent with EK, and cats were treated with a topical corticosteroid (CS) or a topical calcineurin inhibitor (CI). All cats were examined at least twice by a veterinary ophthalmologist. Clinical signs, medication type, and medication frequency were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventeen of 28 cats (61%) were treated with CS, and 11\/28 cats (39%) with CI. Median time to improvement in cats did not differ between CS, 19\u2009days, and CI, 16\u2009days (Mann\u2013Whitney U\u2009=\u200961.5,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.10). Disease was considered controlled at last follow\u2010up, median 91\u2009days, more often with CS (15\/17 cats; 88%) than CI (6\/11 cats; 55%) (X\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20094.0,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Disease control was achieved with treatment once a day or less, more often in CS cats (12\/15; 80%) than CI cats (2\/6; 33%) (X\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20094.2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). There was a high prevalence of corneal ulcers (12\/17 CS cats, 71%; 10\/11 CI cats, 91%), all of which healed regardless of treatment. Acute bullous keratopathy developed in one CS cat and one CI cat.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Initial response to treatment for EK in cats is similar when treated with topical corticosteroids or topical calcineurin inhibitors. Topical corticosteroid treatment may be associated with better control and less frequent medication.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.70202","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:50:57Z","timestamp":1781668257000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Initial Outcomes Following Treatment With Topical Corticosteroids or Topical Calcineurin Inhibitors in Cats With Eosinophilic Keratitis"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8285-3388","authenticated-orcid":false,"given":"Jacklin S.","family":"Pletcher","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Lassaline","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0198-6050","authenticated-orcid":false,"given":"Tiantian","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine","family":"Holt","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"131","article-title":"Feline Eosinophilic Keratitis: A Retrospective Study of 54 Cases:(1989\u20101994)","volume":"6","author":"Morgan V.","year":"1996","journal-title":"Veterinary and Comparative Ophthalmology"},{"key":"e_1_2_9_3_1","first-page":"63","article-title":"Feline Eosinophilic Keratitis: A Review of 15 Clinical Cases","volume":"23","author":"Paulsen M.","year":"1987","journal-title":"Journal of the American Animal Hospital Association"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2008.00679.x"},{"issue":"9","key":"e_1_2_9_5_1","first-page":"1308","article-title":"Eosinophilic Keratoconjunctivitis in a Horse","volume":"205","author":"Ramsey D. 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