{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T09:09:12Z","timestamp":1788944952382,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the clinical presentation, diagnostic findings, and surgical management of zygomatic sialadenitis associated with retrobulbar disease in a dog following extensive dental extractions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals Studied<\/jats:title>\n                    <jats:p>A 10\u2010year\u2010old spayed female Cavalier King Charles Spaniel.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedures<\/jats:title>\n                    <jats:p>The dog was evaluated for acute\u2010onset right\u2010sided exophthalmos that developed after a recent dental procedure involving 15 extractions. Ophthalmic examination identified marked exophthalmos, pain on opening of the mouth, lagophthalmos, and a superficial corneal ulcer. Computed tomography (CT) of the head was performed and revealed a tubular fluid\u2010filled structure likely consistent with a retrobulbar abscess and right\u2010sided zygomatic sialadenitis. Samples for cytology and culture were obtained. Initial medical management included intravenous fluids, broad\u2010spectrum systemic antibiotics, analgesics, topical antibiotics, and ocular antihypertensive medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Cytology revealed septic suppurative inflammation. Microbial culture identified\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Bacteroides pyogenes<\/jats:italic>\n                      <\/jats:styled-content>\n                      , an anaerobic organism not typically associated with antimicrobial resistance. Histopathology confirmed subacute zygomatic sialadenitis with associated cellulitis. Due to progressive clinical deterioration and vision loss, transpalpebral exenteration with zygomatic sialoadenectomy was performed. Postoperative recovery was uneventful, with complete resolution of periocular swelling and pain on follow\u2010up examination.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Zygomatic sialadenitis should be considered a differential diagnosis for retrobulbar disease in dogs, particularly when cases are refractory to medical management. In this case, persistent salivary secretions likely contributed to ongoing inflammation and clinical signs. Advanced imaging facilitated accurate diagnosis, and surgical removal of the affected gland was necessary for definitive resolution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.70257","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T08:34:14Z","timestamp":1787301254000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Zygomatic Sialadenitis as a Rare Cause of Exophthalmos in a Dog"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9163-214X","authenticated-orcid":false,"given":"Katrina E. V.","family":"Jones","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine North Carolina State University  Raleigh North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2009-8232","authenticated-orcid":false,"given":"Manabu","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine North Carolina State University  Raleigh North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8146-068X","authenticated-orcid":false,"given":"Hans D.","family":"Westermeyer","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine North Carolina State University  Raleigh North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4445-7291","authenticated-orcid":false,"given":"Danielle","family":"Meritet","sequence":"additional","affiliation":[{"name":"Molecular Biomedical Sciences, College of Veterinary Medicine North Carolina State University  Raleigh North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"893","volume-title":"Veterinary Ophthalmology","author":"Pot S. A.","year":"2021"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.239.9.1211"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12924"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1978.172.08.940"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13909"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.21.02.0027"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcr2.1314"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.12398"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2007.00569.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2016.10.008"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.21.04.0180"},{"key":"e_1_2_8_13_1","first-page":"103","volume-title":"Slatter's Fundamentals of Veterinary Ophthalmology","author":"Gould D.","year":"2018"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2009.04.005"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.4314\/ovj.v8i4.15"},{"key":"e_1_2_8_16_1","first-page":"143","volume-title":"Veterinary Ophthalmology","author":"Hendrix D. V. H.","year":"2021"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2008.05.001"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2009.00739.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2011.00931.x"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.70257","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vop.70257","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.70257","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T08:46:44Z","timestamp":1788943604000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vop.70257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,21]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/vop.70257"],"URL":"https:\/\/doi.org\/10.1111\/vop.70257","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,21]]},"assertion":[{"value":"2026-05-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70257"}}