{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T08:08:33Z","timestamp":1773043713281,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,7,17]],"date-time":"2014-07-17T00:00:00Z","timestamp":1405555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with abnormal placentation are hospitalized approximately 21\u00a0days prior to scheduled delivery due to risk of peri\u2010partum bleeding. It is required to have at least one red blood cell (<jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>) unit ready throughout hospitalization. This can be accomplished by performing a type and cross (T&amp;C) every 72\u00a0h (traditional method) or providing phenotypically matched <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> units (alternative method).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A Markov\u2010based model was created to compare the cost\u2010benefits between these two methods. A patient either undergoes the traditional or alternative method. If the patient already made an antibody and\/or has rare phenotypes requiring frozen <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> unit at admission, then she can only enter the traditional method. All patients receive a T&amp;C at the end of the 21st day in order to prepare <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> units for scheduled delivery. Model parameters are derived from literature and institutional experiences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Simulation was run for modelling of the 21\u2010day hospitalization of each patient. The expected cost per <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> unit of the traditional method is significantly higher than the alternative method (876\u00b759 vs. 608\u00b732\u00a0<jats:styled-content style=\"fixed-case\">USD<\/jats:styled-content>,<jats:italic> P<\/jats:italic>\u2010value &lt;0\u00b701). For each <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> unit, 4\u00b785\u00a0h of technician working time is saved by the alternative method. However, to be cost\u2010beneficial, the alternative method should be used only if the total cost of a <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> unit is &lt;857\u00b767\u00a0<jats:styled-content style=\"fixed-case\">USD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our model demonstrated that preparing phenotypically matched <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> units at admission is more cost\u2010beneficial comparing to the traditional method of T&amp;C every 72\u00a0h if the cost for the matched unit is &lt;857\u00b767\u00a0<jats:styled-content style=\"fixed-case\">USD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.12176","type":"journal-article","created":{"date-parts":[[2014,7,17]],"date-time":"2014-07-17T04:36:54Z","timestamp":1405571814000},"page":"399-406","source":"Crossref","is-referenced-by-count":7,"title":["Phenotypically matched vs. traditional screen method for preparing red blood cell units in patients with abnormal placentation: a decision analysis approach"],"prefix":"10.1111","volume":"107","author":[{"given":"H. P.","family":"Pham","sequence":"first","affiliation":[{"name":"Department of Pathology University of Alabama at Birmingham Birmingham AL USA"},{"name":"Department of Pathology and Cell Biology Columbia University Medical Center and the New York\u2010Presbyterian Hospital New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. H.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Health Policy Management Mailman School of Public Health Columbia University New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Pathology and Cell Biology Columbia University Medical Center and the New York\u2010Presbyterian Hospital New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,7,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000207559.15715.98"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000219750.79480.84"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.074"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70463-0"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/jmf.13.3.175.190"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2013.06.014"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/OGX.0b013e3182685870"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182051db2"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016349.2010.503869"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181f3588d"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70117-5"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X9301300409"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1993.33393174447.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12250"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027619"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340802268880"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02233.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2010.09.011"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(00)00428-0"},{"key":"e_1_2_8_21_1","unstructured":"AABB:CMS Publishes 2013 Hospital Outpatient Prospective Payment System Rule AABB 2013. Available at:http:\/\/www.aabb.org\/programs\/reimbursementinitiatives\/Pages\/13hoppsrule.aspx(Last accessed 2 February 2014)."},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12270"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2002.00234.x"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvox.12176","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.12176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T14:27:22Z","timestamp":1695997642000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.12176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,17]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/vox.12176"],"URL":"https:\/\/doi.org\/10.1111\/vox.12176","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"value":"0042-9007","type":"print"},{"value":"1423-0410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,17]]}}}