{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T18:07:19Z","timestamp":1780078039602,"version":"3.54.0"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T00:00:00Z","timestamp":1470787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000243","name":"W. Garfield Weston Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000243","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001206","name":"Harvard Club of Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001206","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>The objective of the study was to investigate the splanchnic blood flow velocity and oximetry response to blood transfusion in preterm infants according to postnatal age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Preterm infants receiving blood transfusion were recruited to three groups: 1\u20137 (group 1;<jats:italic>n<\/jats:italic>= 20), 8\u201328 (group 2;<jats:italic>n<\/jats:italic>= 21) and \u226529 days of life (group 3;<jats:italic>n<\/jats:italic>= 18). Superior mesenteric artery (<jats:styled-content style=\"fixed-case\">SMA<\/jats:styled-content>) peak systolic (<jats:styled-content style=\"fixed-case\">PSV<\/jats:styled-content>) and diastolic velocities were measured 30\u201360 min pre\u2010 and post\u2010transfusion using Doppler ultrasound scan. Splanchnic tissue haemoglobin index (<jats:styled-content style=\"fixed-case\">sTHI<\/jats:styled-content>), tissue oxygenation index (<jats:styled-content style=\"fixed-case\">sTOI<\/jats:styled-content>) and fractional tissue oxygen extraction (<jats:styled-content style=\"fixed-case\">sFTOE<\/jats:styled-content>) were measured from 15\u201320 min before to post\u2010transfusion using near\u2010infrared spectroscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean pretransfusion Hb in group 1, 2 and 3 was 11, 10 and 9 g\/dl, respectively. The mean (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) pretransfusion<jats:styled-content style=\"fixed-case\">SMA PSV<\/jats:styled-content>in group 1, 2 and 3 was 0\u00b763 (0\u00b732), 0\u00b781 (0\u00b733) and 0\u00b797 (0\u00b740) m\/s, respectively, and this did not change significantly following transfusion. The mean (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) pretransfusion<jats:styled-content style=\"fixed-case\">sTOI<\/jats:styled-content>in group 1, 2 and 3 was 36\u00b77 (19\u00b73), 44\u00b76 (10\u00b74) and 41\u00b73 (10\u00b74)%, respectively. The<jats:styled-content style=\"fixed-case\">sTHI<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">sTOI<\/jats:styled-content>increased (<jats:italic>P<\/jats:italic>&lt; 0\u00b701), and<jats:styled-content style=\"fixed-case\">sFTOE<\/jats:styled-content>decreased (<jats:italic>P<\/jats:italic>&lt; 0\u00b701) following transfusion in all groups. On multivariate analysis, changes in<jats:styled-content style=\"fixed-case\">SMA PSV<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">sTOI<\/jats:styled-content>following blood transfusion were not associated with<jats:styled-content style=\"fixed-case\">PDA<\/jats:styled-content>, feeding, pretransfusion Hb and mean blood pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pretransfusion baseline splanchnic tissue oximetry and blood flow velocity varied with postnatal age. Blood transfusion improved intestinal tissue oxygenation without altering mesenteric blood flow velocity irrespective of postnatal ages.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.12436","type":"journal-article","created":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T13:18:40Z","timestamp":1470835120000},"page":"399-408","source":"Crossref","is-referenced-by-count":25,"title":["Blood transfusion in preterm infants improves intestinal tissue oxygenation without alteration in blood flow"],"prefix":"10.1111","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7765-8439","authenticated-orcid":false,"given":"J.","family":"Banerjee","sequence":"first","affiliation":[{"name":"Neonatal Unit Homerton University Hospital NHS Foundation Trust London UK"},{"name":"Centre for Paediatrics Barts and the London School of Medicine and Dentistry Queen Mary University of London UK"},{"name":"Portland Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. 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