{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T18:10:25Z","timestamp":1792692625348,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T00:00:00Z","timestamp":1471910400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009741","name":"National Blood Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009741","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background &amp; Objectives<\/jats:title><jats:p>Red blood cells (<jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>s) may be stored up to 42 days before transfusion, per <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">EU<\/jats:styled-content> standards. Although there is ample evidence that <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>s undergo deleterious changes during storage, studies assessing outcomes relative to storage time report conflicting findings. This study investigated <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> storage duration perspectives and practices among blood banking and transfusion professionals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials &amp; Methods<\/jats:title><jats:p>A survey was administered at the American Association of Blood Banking annual meeting in October 2014 (<jats:italic>N<\/jats:italic> = 69).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>On average, participants believed <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> storage should not exceed 34 days (median: 35; range: 1\u201352), and estimated that <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>s are typically stored 21 days before transfusion at their institutions (median: 20; range: 10\u201340). There was 97% agreement that minimizing\/reversing changes during <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> storage may produce clinical benefits; however, 80% believed the research does not consistently demonstrate worse outcomes using older blood. Two\u2010thirds agreed that <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> storage duration is a major concern, but 81% agreed most institutions are not pursuing measures to shorten storage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study found that many transfusion professionals believe <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>s should be stored for fewer than the 42 days currently allowed and that further efforts are warranted to abrogate changes in stored <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content>s. These findings suggest a need for increased awareness of potential consequences of extended <jats:styled-content style=\"fixed-case\">RBC<\/jats:styled-content> storage and for strategies to maximize transfusion benefits.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.12441","type":"journal-article","created":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T19:26:38Z","timestamp":1471980398000},"page":"357-364","source":"Crossref","is-referenced-by-count":25,"title":["Perspectives on the impact of storage duration on blood quality and transfusion outcomes"],"prefix":"10.1111","volume":"111","author":[{"given":"J. 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Last accessed 18 May 2015."},{"key":"e_1_2_8_9_1","unstructured":"Joint United Kingdom Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee:Shelf life of red cells in additive solution (SAG\u2010M).www.transfusionguidelines.org\/document-library\/documents\/shelf-life-of-red-cells-in-additive-solution-sag-m. Published May 2005. Updated September 2014. 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