{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:26:48Z","timestamp":1740126408596,"version":"3.37.3"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T00:00:00Z","timestamp":1507680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"It would be desirable to be able to distinguish fever as a result of febrile non\u2010haemolytic transfusion reactions (FNHTR<\/jats:styled-content>) from other febrile conditions. To further characterize the inflammatory feature of FNHTR<\/jats:styled-content>, we measured a large panel of inflammatory markers in pre\u2010 and posttransfusion plasma samples from patients with and without FNHTR<\/jats:styled-content> following the transfusion of leucoreduced red blood cells. As FNHTR<\/jats:styled-content> patients only displayed a significant increase in IL<\/jats:styled-content>\u20106, we conclude that changes in plasma cytokine levels during FNHTR<\/jats:styled-content> are unlikely to be used diagnostically. An incidental finding of a distinct cytokine pattern in pretransfusion samples from FNHTR<\/jats:styled-content> patients warrants further investigations, as it might be used to characterize the nature of FNHTR<\/jats:styled-content> and to predict the risk of these adverse events.<\/jats:p>","DOI":"10.1111\/vox.12607","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T01:52:44Z","timestamp":1507773164000},"page":"76-79","source":"Crossref","is-referenced-by-count":1,"title":["Changes in circulating inflammatory markers following febrile non\u2010haemolytic transfusion reactions to leucoreduced red cells"],"prefix":"10.1111","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7635-8012","authenticated-orcid":false,"given":"R.","family":"Larsen","sequence":"first","affiliation":[{"name":"Department of Clinical Immunology Naestved Hospital Naestved Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Sandhu","sequence":"additional","affiliation":[{"name":"Department of Congenital Diseases Statens Serum Institut Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. H. H.","family":"Heegaard","sequence":"additional","affiliation":[{"name":"Department of Autoimmunology and Biomarkers Statens Serum Institut Copenhagen Denmark"},{"name":"Department of Clinical Biochemistry and Pharmacology Odense University Hospital Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Ullum","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. H.","family":"von Stemann","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. S.","family":"Nellemann","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. B.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Rigshospitalet Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,11]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2003.08.013"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0041-1132.2004.00609.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2005.052241"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2001000300003"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1423-0410.2002.00159.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3843"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91413-9"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvox.12607","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.12607","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T22:58:28Z","timestamp":1695855508000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.12607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,11]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1111\/vox.12607"],"URL":"https:\/\/doi.org\/10.1111\/vox.12607","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"type":"print","value":"0042-9007"},{"type":"electronic","value":"1423-0410"}],"subject":[],"published":{"date-parts":[[2017,10,11]]}}}