{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T23:05:49Z","timestamp":1780527949629,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T00:00:00Z","timestamp":1527120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The recommended treatment in patients with severe haemophilia is prophylaxis. This prevents bleedings and reduces or delays the haemophilic arthropathy. Adherence defined as the follow\u2010up of the patient to the prescriptions of the health professional to his treatment, both pharmacological and modifications in habits or stylelifes. Adherence rates in haemophilia are better than in other chronic diseases, but there remain reasons for nonadherence. The aim was to see if disease behaviour and disease perception together with coping strategies modulate adherence to treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Multicenter cross\u2010sectional descriptive study. Patients recruited in Units of Hemophilia Hospitals and Regional Haemophilia Associations. Twenty\u2010three patients participated The instruments used are as follows: data sheet, <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036, A36 Hemophilia\u2010Qol, Illness Perception Questionnaire\u2010Revised (<jats:styled-content style=\"fixed-case\">IPQ<\/jats:styled-content>\u2010R), Illness Behavior Questionnaire (<jats:styled-content style=\"fixed-case\">IBQ<\/jats:styled-content>) and Coping Strategies Inventory (<jats:styled-content style=\"fixed-case\">CSI<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">VERITAS<\/jats:styled-content>\u2010Pro.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that 56% of patients with haemophilia are adherent. The most relevant clinical variables were hemarthrosis, diagnosis of arthropathy and presence of any coinfection, as well as family history, labour status and sociodemographic variables. Age was not a relevant variable in adherence. The worst adherence coincides with poorer quality of life and inadequate coping style. Nonadherent patients show greater conviction of disease, perception of cyclicity, more hypochondriacal behaviour towards the illness and perception concern about possible side effects of medication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Adherence in haemophilia requires a more experiential approach and individualized education. It is important that professionals take into account the patient's perception, behaviour and attitude towards the disease to achieve a better adaptation of their coping resources.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.12669","type":"journal-article","created":{"date-parts":[[2018,5,25]],"date-time":"2018-05-25T02:19:41Z","timestamp":1527214781000},"page":"577-583","source":"Crossref","is-referenced-by-count":12,"title":["The behaviour and perception of illness: modulating variables of adherence in patients with haemophilia"],"prefix":"10.1111","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0518-0456","authenticated-orcid":false,"given":"A.","family":"Torres\u2010Ortu\u00f1o","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Social Psychology Faculty of Medicine University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Cuesta\u2010Barriuso","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy School of Biomedical and Health Sciences European University of Madrid Madrid Spain"},{"name":"Royal Foundation Victoria Eugenia Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Nieto\u2010Munuera","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Social Psychology Faculty of Medicine University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Galindo\u2010Pi\u00f1ana","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Social Psychology Faculty of Medicine University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.\u2010A.","family":"L\u00f3pez\u2010Pina","sequence":"additional","affiliation":[{"name":"Department of Basic Psychology and Methodology Faculty of Psychology University of Murcia Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,24]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Federation of Hemophilia. Guidelines Working Group on Behalf of the World Federation of Hemophilia (WFH)[webpage on the Internet].Guidelines for the Management of Haemophilia. 2nd ed. Blackwell Publishing Ltd; 2012. [Available July 6 2012; about 7\u20138 11 59\u201361]. Available from:http:\/\/www1.wfh.org\/publication\/files\/pdf-1472.pdf. [Last accessed 14 August 2015]"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2011.04611.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2007.01625.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067659"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12079"},{"key":"e_1_2_8_7_1","first-page":"49","article-title":"Barriers and perceived limitations to early treatment of hemophilia","volume":"4","author":"Saxeva K","year":"2013","journal-title":"J Blood Med"},{"key":"e_1_2_8_8_1","volume-title":"Adherence to long\u2010term therapies: evidence for action","author":"World Health Organization","year":"2009"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2008.01843.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2006.01189.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12533"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12654"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.13003"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14072"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S126828"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12618"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2009.02094.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2009.02129.x"},{"key":"e_1_2_8_19_1","first-page":"571","volume-title":"Handbook of Health Psychology","author":"Dumbar\u2010Jacob J","year":"2001"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12463"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.13066"},{"key":"e_1_2_8_22_1","first-page":"771","article-title":"La versi\u00f3n espa\u00f1ola del SF\u201036 HealthSurvey (Cuestionario de Salud SF\u201036): un instrumento para la medida de los resultados cl\u0131nicos[Spanish versi\u00f3n of SF\u201036 HealthSurvey: an instrument for measurement clinical outcomes]","volume":"104","author":"Alonso J","year":"1995","journal-title":"Med Clin (Barc)"},{"key":"e_1_2_8_23_1","unstructured":"ArranzP RemorE.Cuestionario Especifico para la Evaluaci\u00f3n de Calidad de Vida Relacionada con la Salud en Pacientes Adultos con Hemofilia(A36 Hemofilia\u2010Qol): manual de utilizaci\u00f3n [Specific Questionnaire for Assessment of the Quality of Life related with Health in adults patients with haemophilia (A36 Hemophilia\u2010Qol): manual of use].Madrid:Baxter BioScience 2005"},{"key":"e_1_2_8_24_1","unstructured":"DiazJL &RemorE.Situaci\u00f3n sociolaboral en Hemofilia[Labour social situation in Hemophilia]. 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