{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T13:07:54Z","timestamp":1765112874309,"version":"3.40.5"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,29]],"date-time":"2019-12-29T00:00:00Z","timestamp":1577577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Sanquin Blood Supply","award":["PPOD 14-15"],"award-info":[{"award-number":["PPOD 14-15"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec><jats:title>Background and objectives<\/jats:title><jats:p>A successful routine RBC alloantibody screening programme should not lead to unnecessary emotional burden during pregnancy due to inadequate counselling on the risk of severe haemolytic disease of the foetus and the newborn (HDFN). Rareness of this disease may result in insufficient knowledge and subsequent inadequate information transfer to women, diagnosed with RBC antibodies. We investigated the current knowledge, views and experiences of Dutch obstetric care providers regarding RBC alloimmunization during pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>We performed a quantitative cross\u2010sectional study, using a structured digital questionnaire to measure knowledge, attitude and practices (KAP) regarding maternal RBC alloimmunization among Dutch obstetric care providers in 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>About 10% of obstetric care providers completed the questionnaire. A sufficient level of knowledge was found in 7% of all participants (N\u00a0=\u00a0329). Knowledge about RhD immunisation and prophylaxis was sufficient in 60% of the responders. Knowledge gaps were found concerning the relevance of non\u2010RhD RBC antibodies, the indications for giving extra RhD prophylaxis and the interpretation of laboratory test results. Healthcare providers estimated their own level of knowledge \u2018sufficient\u2019 (primary\/secondary care) to \u2018good\u2019 (tertiary care), and all participants considered their professional role important within the screening programme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dutch obstetric care providers showed a lack of knowledge regarding maternal RBC immunization. Awareness of the lack of knowledge is necessary to help obstetric care providers to be careful in giving information and even to decide to contact the expert centre before counselling the patient.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.12883","type":"journal-article","created":{"date-parts":[[2019,12,30]],"date-time":"2019-12-30T00:33:59Z","timestamp":1577666039000},"page":"211-220","source":"Crossref","is-referenced-by-count":8,"title":["Knowledge, attitude and practices of obstetric care providers towards maternal red\u2010blood\u2010cell immunization during pregnancy"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8209-7237","authenticated-orcid":false,"given":"Yolentha M.","family":"Slootweg","sequence":"first","affiliation":[{"name":"Department of Obstetrics Leiden University Medical Center Leiden The Netherlands"},{"name":"Department of Clinical Transfusion Research Sanquin Research Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chawa","family":"Walg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0532-0022","authenticated-orcid":false,"given":"Joke M.","family":"Koelewijn","sequence":"additional","affiliation":[{"name":"Department of Clinical Transfusion Research Sanquin Research Leiden The Netherlands"},{"name":"Department of Immunohematology Diagnostics Sanquin Diagnostic Services Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7856-3397","authenticated-orcid":false,"given":"Inge L.","family":"Van Kamp","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masja","family":"De Haas","sequence":"additional","affiliation":[{"name":"Department of Clinical Transfusion Research Sanquin Research Leiden The Netherlands"},{"name":"Department of Immunohematology Diagnostics Sanquin Diagnostic Services Amsterdam The Netherlands"},{"name":"Department of Immunohematology and Blood Transfusion Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,29]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"499","volume-title":"Mollison's blood transfusion in clinical Medicine","author":"Klein HG","year":"2012"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1111\/vox.12265"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1111\/j.1537-2995.2007.01625.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.1056\/NEJMra1308124"},{"doi-asserted-by":"publisher","key":"e_1_2_9_6_1","DOI":"10.1038\/pr.2013.208"},{"key":"e_1_2_9_7_1","first-page":"207","article-title":"Fetal anemia due to non\u2010Rhesus\u2010D red\u2010cell alloimmunization; Seminars in fetal and neonatal medicine","volume":"13","author":"Moise KJ","year":"2008","journal-title":"Perinat Haematol"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1111\/j.1537-2995.2008.01742.x"},{"doi-asserted-by":"publisher","key":"e_1_2_9_9_1","DOI":"10.1136\/fn.88.1.F6"},{"doi-asserted-by":"publisher","key":"e_1_2_9_10_1","DOI":"10.1111\/1471-0528.13816"},{"volume-title":"Guideline Blood Transfusion","year":"2011","author":"CBO","key":"e_1_2_9_11_1"},{"volume-title":"Prenatal screening infectious diseases and erythrocyte antibodies","year":"2014","author":"RIVM","key":"e_1_2_9_12_1"},{"doi-asserted-by":"publisher","key":"e_1_2_9_13_1","DOI":"10.1067\/mob.2001.112970"},{"doi-asserted-by":"publisher","key":"e_1_2_9_14_1","DOI":"10.1016\/j.ajog.2018.07.020"},{"doi-asserted-by":"publisher","key":"e_1_2_9_15_1","DOI":"10.1056\/NEJMoa052855"},{"doi-asserted-by":"publisher","key":"e_1_2_9_16_1","DOI":"10.1002\/pd.2551"},{"doi-asserted-by":"publisher","key":"e_1_2_9_17_1","DOI":"10.1002\/uog.17319"},{"doi-asserted-by":"publisher","key":"e_1_2_9_18_1","DOI":"10.1080\/17474086.2017.1305265"},{"doi-asserted-by":"publisher","key":"e_1_2_9_19_1","DOI":"10.1186\/1471-2393-8-49"},{"doi-asserted-by":"publisher","key":"e_1_2_9_20_1","DOI":"10.1002\/pd.4135"},{"key":"e_1_2_9_21_1","first-page":"1054","article-title":"The use of anti\u2010D immunoglobulins for rhesus prophylaxis: audit on knowledge and practices among obstetricians","volume":"50","author":"Wee WW","year":"2009","journal-title":"Singapore Med J"},{"doi-asserted-by":"publisher","key":"e_1_2_9_22_1","DOI":"10.1371\/journal.pone.0091013"},{"key":"e_1_2_9_23_1","first-page":"16","article-title":"Prenatale screening en de non\u2010invasieve prenatale test: hoe denken eerstelijns verloskundigen erover? (English translation: Prenatal screening and the non\u2010invasive prenatal test: How do midwives think about it?)","volume":"1","author":"Verweij EJ","year":"2015","journal-title":"Tijdschrift voor Verloskundigen"},{"doi-asserted-by":"publisher","key":"e_1_2_9_24_1","DOI":"10.5688\/ajpe816106"},{"doi-asserted-by":"publisher","key":"e_1_2_9_25_1","DOI":"10.1027\/1614-2241\/a000014"},{"unstructured":"Ploeg CSY OomenP VosK:Most important findings of national screening infection diseases and red blood cell immunisation in pregnancy of 2016. 2018\u201007\u201023 RIVM National Institute for Public Health and the Environment 2016.","key":"e_1_2_9_26_1"},{"doi-asserted-by":"publisher","key":"e_1_2_9_27_1","DOI":"10.1186\/s12887-017-0873-1"},{"doi-asserted-by":"publisher","key":"e_1_2_9_28_1","DOI":"10.1038\/gim.2011.5"},{"doi-asserted-by":"publisher","key":"e_1_2_9_29_1","DOI":"10.1001\/archpediatrics.2011.696"},{"doi-asserted-by":"publisher","key":"e_1_2_9_30_1","DOI":"10.1177\/1367493512443906"},{"doi-asserted-by":"publisher","key":"e_1_2_9_31_1","DOI":"10.1016\/j.srhc.2010.05.001"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvox.12883","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.12883","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vox.12883","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.12883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T18:55:03Z","timestamp":1694026503000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.12883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,29]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1111\/vox.12883"],"URL":"https:\/\/doi.org\/10.1111\/vox.12883","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"type":"print","value":"0042-9007"},{"type":"electronic","value":"1423-0410"}],"subject":[],"published":{"date-parts":[[2019,12,29]]}}}