{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:49:49Z","timestamp":1790696989580,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The objectives of this study are to estimate the prevalence of iron deficiency (ID) among French whole\u2010blood (WB) donors to identify factors associated with ID and to generate decision trees.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design and methods<\/jats:title>\n                    <jats:p>A prospective National multicentre study was performed on WB donors from March 11, to April 5th, 2019. Samples were selected randomly to perform serum ferritin. ID was defined as ferritin value under 26\u00a0ng\/ml. All results were stratified by sex. Factors associated with ID were analysed using multivariate logistic regression model. CART algorithm was used for decision trees.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven thousand two hundred fifty eight WB donors were included. ID was more frequent in women (39\u00b75%) than in men (18\u00b70%). Among 7200 repeated donors, women below 50\u00a0yo had a higher risk (OR\u00a0=\u00a02\u00b737; [1\u00b797\u20132\u00b785] IC95) than those above 50\u00a0yo. Factors associated with ID were: haemoglobin level under the threshold at donation n\u20101 except for women and n\u20102 donation; a low mean corpuscular haemoglobin at n\u20101 and n\u20102 donations; a shorter interval since n\u20101 donation and between n\u20101 and n\u20102 donations except for women; and women who had given three or four times in the last year. CART algorithm defined high risk of ID subgroups within three populations of donors, new female donors, repeated male donors and repeated female donors. In these identified subgroups, prevalence of ID was up to 72\u00b71%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study showed the high prevalence of ID among French WB donors, identified well\u2010known and new factors associated with ID and defined algorithms predicting ID in three populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.12991","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T08:48:34Z","timestamp":1600850914000},"page":"42-52","source":"Crossref","is-referenced-by-count":18,"title":["Iron deficiency among French whole\u2010blood donors: first assessment and identification of predictive factors"],"prefix":"10.1111","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7268-4160","authenticated-orcid":false,"given":"Anne\u2010Marie","family":"Fillet","sequence":"first","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Martinaud","sequence":"additional","affiliation":[{"name":"Centre de Transfusion Sanguine des Arm\u00e9es Clamart France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Malard","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Le Cam","sequence":"additional","affiliation":[{"name":"Etablissent Fran\u00e7ais du sang Blood Biological Qualification Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Hejl","sequence":"additional","affiliation":[{"name":"Laboratory Medicine Department Military Medical Center Percy Clamart France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Chenus","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevi\u00e8ve","family":"Woimant","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Chueca","sequence":"additional","affiliation":[{"name":"Centre de Transfusion Sanguine des Arm\u00e9es Clamart France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Jacquot","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Besiers","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Morel","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachid","family":"Djoudi","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliane","family":"Garrab\u00e9","sequence":"additional","affiliation":[{"name":"Centre de Transfusion Sanguine des Arm\u00e9es Clamart France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Gross","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,23]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"WHO:Voluntary non\u2010remunerated blood donation[Internet].WHO. [cited 2019 Dec 16]. Available from:http:\/\/www.who.int\/bloodsafety\/voluntary_donation\/en\/"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32156-6"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2007.00818.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/62.3.611"},{"key":"e_1_2_8_6_1","unstructured":"Journal Officiel.Arret\u00e9 du 5 avril 2016 fixant les crit\u00e8res de s\u00e9lection des donneurs de sang. AFSP1608360A"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12563"},{"key":"e_1_2_8_8_1","first-page":"20","article-title":"International forum: an investigation of iron status in blood donors","volume":"15","author":"Vuk T","year":"2017","journal-title":"Blood Transfus"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/66.2.334"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15509"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12518"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3148.1999.00191.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2015.03.020"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03401.x"},{"key":"e_1_2_8_15_1","unstructured":"WHO.Serum ferritin concentrations for the assessment of iron status and iron deficiency in populations. Concentrations s\u00e9riques de ferritine permettant d\u2019\u00e9valuer le statut et les carences en fer dans les populations [Internet]. 2011 [cited 2020 Jul 6]; Available from:https:\/\/apps.who.int\/iris\/handle\/10665\/85843"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12408"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12380"},{"key":"e_1_2_8_18_1","unstructured":"Sant\u00e9 publique France:Study of health on environnement biosurveillance physical activity and nutrition (Esteban) 2014\u20132016. Nutrition portion. Chapter biological dosages: vitamines and mineral. Saint\u2010Maurice: Sant\u00e9 publique France 2019. 61p. [Internet]. [cited 2020 Feb 4]. Available from:https:\/\/www.santepubliquefrance.fr\/determinants\u2010de\u2010sante\/nutrition\u2010et\u2010activite\u2010physique\/documents\/rapport\u2010synthese\/etude\u2010de\u2010sante\u2010sur\u2010l\u2010environnement\u2010la\u2010biosurveillance\u2010l\u2010activite\u2010physique\u2010et\u2010la\u2010nutrition\u2010esteban\u20102014\u20102016\u2010.\u2010volet\u2010nutrition.\u2010chapitre\u2010dosages"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14921"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15448"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2017004820"},{"issue":"3","key":"e_1_2_8_22_1","first-page":"3A","article-title":"Factors associated with the recovery of haemoglobin levels after whole\u2010blood donation \u2010 haemoglobin and return to blood donation of prospective donors in continental France in 2015","volume":"57","author":"Fillet A\u2010M","year":"2017","journal-title":"Transfusion"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15179"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-04-709451"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14941"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14226"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13152"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14173"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03956.x"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.12991","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vox.12991","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.12991","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T04:59:59Z","timestamp":1693198799000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.12991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,23]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/vox.12991"],"URL":"https:\/\/doi.org\/10.1111\/vox.12991","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"value":"0042-9007","type":"print"},{"value":"1423-0410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,23]]}}}