{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T02:56:19Z","timestamp":1774407379646,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T00:00:00Z","timestamp":1634083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004351","name":"Sultan Qaboos University","doi-asserted-by":"publisher","award":["IG\/MED\/HEAM\/18\/01"],"award-info":[{"award-number":["IG\/MED\/HEAM\/18\/01"]}],"id":[{"id":"10.13039\/501100004351","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Blood group genotyping has been used in different populations. This study aims at evaluating the genotypes of common blood group antigens in the Omani blood donors and to assess the concordance rate with obtained phenotypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Blood samples from 180 Omani donors were evaluated. Samples were typed by serological methods for the five blood group systems MNS, RH (RHD\/RHCE), KEL, FY and JK. Samples were genotyped using RBC\u2010FluoGene vERYfy eXtend kit (inno\u2010train\u00a9). Predicted phenotypic variants for 70 red blood cell antigens among the MNS, RH (RHD\/RHCE), KEL, FY, JK, DO, LU, YT, DI, VEL, CO and KN blood group systems were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Simultaneous phenotype and genotype results were available in 130 subjects. Concordance rate was &gt;95% in all blood group systems with exception of Fy(b+) (87%). Homozygous GATA\u20101 mutation leading to erythroid silencing <jats:italic>FY*02N.01<\/jats:italic> (resulting in the Fy(b\u2010)<jats:sup>ES<\/jats:sup> phenotype) was detected in 81\/112 (72%) of genotyped samples. In addition, discrepant Fy<jats:sup>b<\/jats:sup> phenotype\/genotype result was obtained in 14\/112 samples; 13 of which has a heterozygous GATA\u20101 mutation and one sample with a wild GATA genotype. D and partial e c.733C&gt;G variants expressing the V+VS+ phenotype were found in 22\/121 (18.2%) and 14\/120 (11.7%) of the samples, respectively. Di(a\u2010b+), Js(a\u2010b+), Yt(a+b\u2010) and Kn(a+b\u2010) genotype frequencies were 99.4%, 95.8%, 91.9% and 97.7%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In conclusion, we report a high frequency of <jats:italic>FY*02N.01<\/jats:italic> allele due to homozygous c.\u201067T&gt;C GATA\u20101 single\u2010nucleotide variation. This is the first study reporting the detailed distribution of common and rare red cell genotypes in Omani blood donors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13204","type":"journal-article","created":{"date-parts":[[2021,10,15]],"date-time":"2021-10-15T05:42:32Z","timestamp":1634276552000},"page":"424-430","source":"Crossref","is-referenced-by-count":6,"title":["Molecular blood group screening in Omani blood donors"],"prefix":"10.1111","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8649-0650","authenticated-orcid":false,"given":"Arwa Z.","family":"Al\u2010Riyami","sequence":"first","affiliation":[{"name":"Department of Haematology Sultan Qaboos University Hospital  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Al Hinai","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Sciences Sultan Qaboos University  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Al\u2010Rawahi","sequence":"additional","affiliation":[{"name":"Department of Haematology, College of Medicine and Health Sciences Sultan Qaboos University  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saif","family":"Al\u2010Hosni","sequence":"additional","affiliation":[{"name":"Department of Haematology Sultan Qaboos University Hospital  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoaib","family":"Al\u2010Zadjali","sequence":"additional","affiliation":[{"name":"Sultan Qaboos Comprehensive Cancer Centre  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Al\u2010Marhoobi","sequence":"additional","affiliation":[{"name":"Department of Haematology, College of Medicine and Health Sciences Sultan Qaboos University  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2937-8838","authenticated-orcid":false,"given":"Murtadha","family":"Al\u2010Khabori","sequence":"additional","affiliation":[{"name":"Department of Haematology, College of Medicine and Health Sciences Sultan Qaboos University  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamad","family":"Al\u2010Riyami","sequence":"additional","affiliation":[{"name":"Department of Genetics, College of Medicine and Health Sciences Sultan Qaboos University  Muscat Oman"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8727-1679","authenticated-orcid":false,"given":"Gregory A.","family":"Denomme","sequence":"additional","affiliation":[{"name":"Diagnostic Laboratories Versiti Blood Center of Wisconsin  Milwaukee Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-297"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2007.12.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2016.05.011"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2010.12.010"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2000.40010048.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12623"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3148.2001.00320.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/iji.12354"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-008-0036-0"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14508"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2014.04.009"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.5001\/omj.2019.92"},{"key":"e_1_2_7_14_1","unstructured":"ISBT.Red cell immunogenetics and blood group terminology. 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