{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:39:27Z","timestamp":1790617167493,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T00:00:00Z","timestamp":1644883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Timely and adequate access to safe blood forms an integral part of universal health coverage, but it may be compromised by natural or man\u2010made disasters. This systematic review provides an overview of the best available scientific evidence on the impact of disasters on blood donation rates and safety outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Five databases (The Cochrane Library, MEDLINE, Embase, Web of Science and CINAHL) were searched until 27 March 2020 for (un)controlled studies investigating the impact of disasters on blood donation rates and\/or safety. Risk of bias and overall certainty of the evidence were assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighteen observational studies were identified, providing very low certainty of evidence (due to high risk of bias, inconsistency and\/or imprecision) on the impact of natural (12 studies) and man\u2010made\/technological (6 studies) disasters. The available evidence did not enable us to form any generalizable conclusions on the impact on blood donation rates. Meta\u2010analyses could not detect any statistically significant changes in transfusion\u2010transmissible infection (TTI) rates [hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV)\u20101\/2, human T\u2010lymphotropic virus I and II (HTLV\u2010I\/II) and syphilis] in donated blood after a disaster, either in first\u2010time or repeat donors, although the evidence is very uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The very low certainty of evidence synthetized in this systematic review indicates that it is very uncertain whether there is an association between disaster occurrence and changes in TTI rates in donated blood. The currently available evidence did not allow us to draw generalizable conclusions on the impact of disasters on blood donation rates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.13255","type":"journal-article","created":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T15:57:58Z","timestamp":1644940678000},"page":"769-779","source":"Crossref","is-referenced-by-count":25,"title":["Impact of disasters on blood donation rates and blood safety: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6695-6019","authenticated-orcid":false,"given":"Jorien","family":"Laermans","sequence":"first","affiliation":[{"name":"Centre for Evidence\u2010Based Practice Belgian Red Cross  Mechelen Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorien","family":"O","sequence":"additional","affiliation":[{"name":"Centre for Evidence\u2010Based Practice Belgian Red Cross  Mechelen Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Van den Bosch","sequence":"additional","affiliation":[{"name":"International Cooperation Belgian Red Cross  Mechelen Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4498-9781","authenticated-orcid":false,"given":"Emmy","family":"De Buck","sequence":"additional","affiliation":[{"name":"Centre for Evidence\u2010Based Practice Belgian Red Cross  Mechelen Belgium"},{"name":"Department of Public Health and Primary Care, Faculty of Medicine KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veerle","family":"Compernolle","sequence":"additional","affiliation":[{"name":"Belgian Red Cross, Blood Services  Mechelen Belgium"},{"name":"Faculty of Medicine and Health Sciences Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eilat","family":"Shinar","sequence":"additional","affiliation":[{"name":"National Blood Services Magen David Adom  Tel Aviv Israel"},{"name":"Ben\u2010Gurion University of the Negev  Beer Sheva Israel"},{"name":"Global Advisory Panel on Corporate Governance and Risk Management of Blood Services in Red Cross and Red Crescent Societies (GAP)  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Vandekerckhove","sequence":"additional","affiliation":[{"name":"Department of Public Health and Primary Care, Faculty of Medicine KU Leuven  Leuven Belgium"},{"name":"Global Advisory Panel on Corporate Governance and Risk Management of Blood Services in Red Cross and Red Crescent Societies (GAP)  Perth Australia"},{"name":"Belgian Red Cross  Mechelen Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,15]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organization.WHO model lists of essential medicines. 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