{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T21:54:45Z","timestamp":1776376485406,"version":"3.51.2"},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:00:00Z","timestamp":1666137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Donor criteria for diabetes vary significantly. We describe our evolving policies for donors with diabetes, their contribution to the Canadian blood supply and their rate of syncopal reactions compared to other donors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>All donors are asked if they have diabetes and have taken medications in the last 3\u2009days. We assessed donors with diabetes on various medications, the number deferred over time, and syncopal reactions in donors with diabetes and other donors in our donor reaction database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Policy changes allowing type 2 diabetic donors on oral hypoglycaemics alone, type 2 diabetic donors on oral medications and insulin and type 1 diabetic donors (all on insulin) to donate resulted in a decrease in deferrals from 450 to 22 donors annually. Of donors being treated with medication for diabetes, 11% are receiving insulin as part of their treatment. Syncopal reaction rates were low and not statistically different between diabetic and non\u2010diabetic donors, although confidence intervals (CIs) are large.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Policies decreased deferrals while maintaining safety. A longer observation period would strengthen these observations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13370","type":"journal-article","created":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T08:58:52Z","timestamp":1666169932000},"page":"1415-1419","source":"Crossref","is-referenced-by-count":2,"title":["Evolving policies for donors with diabetes: The Canadian experience"],"prefix":"10.1111","volume":"117","author":[{"given":"Owen","family":"Miller","sequence":"first","affiliation":[{"name":"Medical Affairs and Innovation Canadian Blood Services Ottawa Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niamh","family":"Caffrey","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation Canadian Blood Services Ottawa Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation Canadian Blood Services Ottawa Canada"},{"name":"School of Epidemiology and Public Health University of Ottawa Ottawa Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9904-9952","authenticated-orcid":false,"given":"Mindy","family":"Goldman","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation Canadian Blood Services Ottawa Canada"},{"name":"Department of Pathology and Laboratory Medicine University of Ottawa Ottawa Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,10,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(21)00113-3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13281"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13308"},{"key":"e_1_2_8_5_1","unstructured":"Recommendations to reduce the possible risk of transmission of Creutzfeldt\u2010Jacob Disease and Variant Creutzfeldt\u2010Jacob Disease by blood and blood components. FDA Guidance for Industry. 2022 May [cited 2022 Aug 10]. Available from:https:\/\/www.fda.gov\/vaccines-blood-biologics\/guidance-compliance-regulatory-information-biologics\/biologics-guidances"},{"key":"e_1_2_8_6_1","unstructured":"New York Blood Center Can I Donate Blood Medical Conditions. [cited 2022 Aug 10]. Available from:https:\/\/www.nybc.org\/donate-blood\/become-donor\/can-i-donate-blood\/"},{"key":"e_1_2_8_7_1","unstructured":"Commission Directive 2004\/33\/\/EC of 22 March 2004. [cited 2022 Aug 10]. Available from:https:\/\/eurlex.europa.eu\/LexUriServ\/LexUriServ.do?uri=OJ:L:2004:091:0025:0039:EN:PDF"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14307"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.24095\/hpcdp.39.11.03"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2009.01275.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03143.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/vox.12739","article-title":"Platelet storage properties are associated with donor age: in vitro quality of platelets from younger donors and older donors with and without type 2 diabetes","volume":"114","author":"Bontekoe IJ","year":"2018","journal-title":"Vox Sang"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.13370","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vox.13370","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.13370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T03:42:46Z","timestamp":1701229366000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.13370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,19]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/vox.13370"],"URL":"https:\/\/doi.org\/10.1111\/vox.13370","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"value":"0042-9007","type":"print"},{"value":"1423-0410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,19]]}}}