{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T03:37:33Z","timestamp":1781840253934,"version":"3.54.5"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T00:00:00Z","timestamp":1669334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010481","name":"Etablissement Fran\u00e7ais du Sang","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010481","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Implementing a ferritin testing policy for whole blood (WB) donors may prevent iron deficiency (ID, ferritin &lt;26\u2009ng\/mL) and anaemia, but may induce donation losses. As part of a national prevention plan in France, we aimed to estimate its impact on ID, anaemias and WB donations among donors at high risk of ID.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A micro\u2010simulation model was developed to evaluate different scenarios compared to the current situation without ferritin testing as a reference scenario. The following scenarios were simulated: a minimum scenario with a 6\u2010month deferral for donors with absent iron store (AIS, ferritinemia &lt;15\u2009ng\/ml), a main scenario with additional delayed invitations for donors with ferritinemia 15\u201325\u2009ng\/ml and a supplementation scenario with additional iron supplementation for 50% of the donors with AIS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the main scenario, 52,699 WB donations per year were estimated to be lost after 1 year (\u22128%), falling to 27,687 (\u22124.7%) after 5\u2009years. IDs and anaemias were reduced by 13.6% and 29.3%, respectively, after 1\u2009year. The supplementation scenario increased the number of prevented IDs and anaemias to 24.1% and 35.4%, respectively, after 1 year, and halved the number of anaemias at 5\u2009years. The latter scenario also had the least impact on the number of donations (\u22123.2% after 5\u2009years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A ferritin testing policy resulting in delayed donations for ID donors is effective in reducing IDs and anaemias, but significantly impacts the number of donations, thereby posing a self\u2010sufficiency challenge.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13377","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T15:39:31Z","timestamp":1669390771000},"page":"24-32","source":"Crossref","is-referenced-by-count":14,"title":["Impact of donor ferritin testing on iron deficiency prevention and blood availability in France: A cohort simulation study"],"prefix":"10.1111","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1864-3824","authenticated-orcid":false,"given":"Pascale","family":"Richard","sequence":"first","affiliation":[{"name":"Medical Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Marie","family":"Fillet","sequence":"additional","affiliation":[{"name":"Medical Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Malard","sequence":"additional","affiliation":[{"name":"Medical Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Leclerc","sequence":"additional","affiliation":[{"name":"Blood Product Collection Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Chanut","sequence":"additional","affiliation":[{"name":"Innovation and Projects Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevi\u00e8ve","family":"Woimant","sequence":"additional","affiliation":[{"name":"Medical Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Jacquot","sequence":"additional","affiliation":[{"name":"Blood Product Collection Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri","family":"Leleu","sequence":"additional","affiliation":[{"name":"Public Health Expertise  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Morel","sequence":"additional","affiliation":[{"name":"Medical Department Etablissement Fran\u00e7ais du Sang  la Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Vimont","sequence":"additional","affiliation":[{"name":"Public Health Expertise  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2007.00818.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12563"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(21)00168-X"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15906"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13126"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12991"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.119"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-04-709451"},{"key":"e_1_2_8_10_1","volume-title":"Study of health on environnement, biosurveillance, physical activity and nutrition (Esteban), 2014\u20132016. 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