{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:20:07Z","timestamp":1787016007510,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>No systematic study has measured the incidence of adverse reactions (ARs) to blood donation at the national level in China before 2019. The objective of this study was to establish an effective reporting system to collect information on ARs to blood donation in China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>The status of donor haemovigilance (DHV) in blood collection facilities in China was evaluated, and an online DHV system was established to collect data on ARs to blood donation in July 2019. The definitions of ARs were based on the International Society of Blood Transfusion (ISBT) standards. The prevalence and data quality of ARs from 2019 to 2021 were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A standard online reporting system has been established for ARs to blood donation. In total, 61, 62 and 81 participating sites were included in this pilot study in 2019, 2020 and 2021, respectively. From July 2019 to December 2021, 21,502 cases of whole\u2010blood\u2010related ARs and 1114 cases of apheresis platelet\u2010related ARs were reported, with an incidence of 3.8\u2030 and 2.2\u2030, respectively. Data completeness for key reporting elements improved from 41.7% (15\/36) in 2019 to 74.4% (29\/39) in 2020. Data quality analysis for the year 2021 yielded similar results as for 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The construction and continuous improvement of the blood donor safety monitoring system prompted the establishment of the DHV system. Improvements have been made to the DHV system in China, with a significant increase in sentinels and higher data quality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.13421","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T03:12:57Z","timestamp":1678417977000},"page":"357-366","source":"Crossref","is-referenced-by-count":4,"title":["First donor haemovigilance system at a national level in China: Establishment and improvement"],"prefix":"10.1111","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9438-7493","authenticated-orcid":false,"given":"Junhong","family":"Yang","sequence":"first","affiliation":[{"name":"Chongqing Blood Center  Chongqing China"},{"name":"Working Party on Hemovigilance of the Chinese Society of Blood Transfusion  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinrong","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Nursing Chongqing Medical University  Chongqing China"},{"name":"Department of Critical Care Medicine The Second Affiliated Hospital of Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongfu","family":"Xie","sequence":"additional","affiliation":[{"name":"Working Party on Hemovigilance of the Chinese Society of Blood Transfusion  Chongqing China"},{"name":"Shanghai Red Cross Blood Center  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojie","family":"Guo","sequence":"additional","affiliation":[{"name":"Working Party on Hemovigilance of the Chinese Society of Blood Transfusion  Chongqing China"},{"name":"Anhui Blood Center  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqing","family":"Zhu","sequence":"additional","affiliation":[{"name":"Fujian Blood Center  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"He","sequence":"additional","affiliation":[{"name":"Working Party on Hemovigilance of the Chinese Society of Blood Transfusion  Chongqing China"},{"name":"Chongqing Society of Blood Tranfusion  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Huang","sequence":"additional","affiliation":[{"name":"Chongqing Blood Center  Chongqing China"},{"name":"Working Party on Hemovigilance of the Chinese Society of Blood Transfusion  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118338179.ch24"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2011.12.003"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/voxs.12090"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12447"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13048"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13059"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/voxs.12091"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12582"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12323"},{"key":"e_1_2_9_11_1","unstructured":"China's Ministry of Health: guidelines on the classification of blood donation adverse reaction (WS\/T 551\u20132017). [cited 2022 Oct 11]. Available from:http:\/\/www.nhc.gov.cn\/ewebeditor\/uploadfile\/2017\/05\/20170517142610845.pdf. Accessed 11 Mar 2018."},{"key":"e_1_2_9_12_1","unstructured":"AABB Donor Hemovigilance Working Group: 2012\u20132017 AABB Donor Hemovigilance Highlights. [cited 2022 Oct 11]. Available from:https:\/\/www.aabb.org\/docs\/default-source\/default-document-library\/resources\/2012-2017-aabb-donor-hemovigilance-highlights.pdf. Accessed 25 Jan 2020."},{"key":"e_1_2_9_13_1","unstructured":"ANNUAL SHOT REPORT 2021. [cited 2022 Oct 11]. Available from:https:\/\/www.shotuk.org\/wp-content\/uploads\/myimages\/SHOT-REPORT-2021-FINAL-bookmarked.pdf. Accessed 13 Jul 2022."},{"key":"e_1_2_9_14_1","first-page":"281","article-title":"Vasovagal reactions in whole blood and apheresis donors: a cross\u2010sectional study on donor haemovigilance data from 2016 to 2019 in Italy","volume":"20","author":"Piccinini V","year":"2022","journal-title":"Blood Transfus"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2016.12.002"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15442"},{"key":"e_1_2_9_17_1","unstructured":"IHN: International Surveillance of Transfusion\u2010Associated Reactions and Events (ISTARE). [cited 2022 Oct 11]. Available at:https:\/\/www.ihn-org.com\/istare\/access-to-istare\/. Accessed 14 Mar 2021."},{"key":"e_1_2_9_18_1","unstructured":"WHO: a guide to establishing a national haemovigilance system [internet]. Geneva. 2016 [cited 2022 Oct 15]. Available from:https:\/\/www.who.int\/bloodsafety\/haemovigilance\/haemovigilance-guide\/en\/"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14948"},{"key":"e_1_2_9_20_1","unstructured":"Australian Haemovigilance Report \u2010 Data for 2018\u201319. [cited 2022 Oct 11]. Available from:https:\/\/www.blood.gov.au\/system\/files\/documents\/Australian-Haemovigilance-Report-2018-19-FINAL_v2.pdf"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16099"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12981"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2012.01659.x"},{"key":"e_1_2_9_24_1","unstructured":"AABB Donor Hemovigilance Working Group: the 2012\u20132014 AABB Donor Hemovigilance Report. [cited 2022 Oct 11]. Available from:http:\/\/www.aabb.org\/research\/hemovigilance\/Documents\/2012-2014-AABB-Donor-Hemovigilance-Report.pdf"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15830"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15854"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.13421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vox.13421","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.13421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T08:12:57Z","timestamp":1692432777000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.13421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,9]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1111\/vox.13421"],"URL":"https:\/\/doi.org\/10.1111\/vox.13421","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"value":"0042-9007","type":"print"},{"value":"1423-0410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,9]]}}}