{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T14:50:26Z","timestamp":1788447026801,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T00:00:00Z","timestamp":1684022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Since the advent of AIDS, men who have sex with men (MSM) have often been deferred from blood donation. In France, quarantine plasma donation by MSM donors with the same deferral rules as for other donors was introduced in July 2016 and continued up to March 2022. At this time, MSM\u2010specific deferral criteria were lifted for all blood or plasma donation. The donor deferral, as well as rate of infectious markers in plasma donors who would have been otherwise deferred for MSM activity, was evaluated and compared with those of the other donors during the same time period from June 2016 to March 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 8843 MSM donors made 12,250 plasma donation applications. The overall deferral rate was very high (75.2%), mainly due to the absence of apheresis capacity at the donation site. The deferral criteria for sexual risk were present in 12.1% of MSM donors compared with 1.0% in other plasma and blood donors (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Overall, 994 MSM donors made 2880 plasma donations. Of these,\u00a0one donation was HIV positive (34.7 vs. 0.6\/10<jats:sup>5<\/jats:sup> donations by other donors, relative risk [RR]: 61.0 [95% confidence interval [CI]: 8.5\u2013437.7]), one was HBV positive (34.7 vs. 4.5\/10<jats:sup>5<\/jats:sup>, RR: 7.7 [95% CI: 1.1\u201354.6]) and none were HCV positive (0 vs. 2.4\/10<jats:sup>5<\/jats:sup>). Additionally, 21 donations were syphilis positive (729.2 vs. 10.7\/10<jats:sup>5<\/jats:sup>, RR: 67.9 [95% CI: 44.2\u2013104.4]). A post hoc analysis of eligible MSM donors who were unable to donate plasma due to logistic constraints yielded similar findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Plasma donation by donors who would have been otherwise deferred for MSM activity was associated with both an increased deferral rate for sexual risk and an increased rate of infectious markers, notably syphilis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13435","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T05:49:40Z","timestamp":1684129780000},"page":"440-446","source":"Crossref","is-referenced-by-count":9,"title":["Evolving deferral criteria for blood donation in France: Plasma donation by men who have sex with men"],"prefix":"10.1111","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9310-8322","authenticated-orcid":false,"given":"Pierre","family":"Tiberghien","sequence":"first","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"},{"name":"UMR RIGHT 1098 Inserm, Universit\u00e9 de Franche\u2010Comt\u00e9 Etablissement Fran\u00e7ais du Sang  Besan\u00e7on France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3322-3580","authenticated-orcid":false,"given":"Sophie","family":"Lecam","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Huet","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Malard","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan","family":"Tavenard","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josiane","family":"Pillonel","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Publique France  Saint\u2010Maurice France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1664-9691","authenticated-orcid":false,"given":"Claire","family":"Sauvage","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Publique France  Saint\u2010Maurice France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaut","family":"Bocquet","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Bliem","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Morel","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"},{"name":"UMR RIGHT 1098 Inserm, Universit\u00e9 de Franche\u2010Comt\u00e9 Etablissement Fran\u00e7ais du Sang  Besan\u00e7on France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1864-3824","authenticated-orcid":false,"given":"Pascale","family":"Richard","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6497-0108","authenticated-orcid":false,"given":"Syria","family":"Laperche","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang  La Plaine Saint\u2010Denis France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-11-833996"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000275"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13541"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMms1613425"},{"key":"e_1_2_9_6_1","unstructured":"French Health Ministry.April 5th 2016 decree establishing blood donor selection criteria (Legifrance) [cited 2023 Feb 1]. 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