{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:56:26Z","timestamp":1780631786590,"version":"3.54.1"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:00:00Z","timestamp":1718236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p><jats:italic>Trypanosoma cruzi<\/jats:italic> is the etiologic agent of Chagas disease (CD), an anthropozoonosis from the American continent that progresses from an acute phase to an indeterminate phase, followed by a chronic symptomatic phase in around 30% of patients. In countries where <jats:italic>T. cruzi<\/jats:italic> is not endemic, many blood transfusion services test blood donors who have stayed in an endemic country (\u2018at\u2010risk stay\u2019)\u2014even if they do not present with other risk factors. However, the efficiency of this approach has been questioned.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>On 18 September 2023, a worldwide survey was distributed among employees of blood transfusion services. The questions mainly pertained to CD's endemicity in the blood services' region, the current testing policy for <jats:italic>T. cruzi<\/jats:italic> and the number of confirmed positive results among donors with a prior at\u2010risk stay <jats:italic>alone<\/jats:italic> (i.e., without other risk factors for <jats:italic>T. cruzi<\/jats:italic> infection).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010six recipients completed the survey. Of the 22 (84.6%) blood services that operated in a non\u2010endemic region, 9 (42.9%) tested donors for <jats:italic>T. cruzi<\/jats:italic>, including 8 (88.9%) that considered the travel history or the duration of the stay (<jats:italic>alone<\/jats:italic>) in their testing algorithm (\u2018study blood services\u2019). Over 93\u2009years of observation among all study blood services, 2 donations from donors with an at\u2010risk stay <jats:italic>alone<\/jats:italic> and 299 from those with other risk factors were confirmed positive for <jats:italic>T. cruzi<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study findings question the utility of testing blood donors who have stayed in an endemic country without other risk factors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13692","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T06:54:28Z","timestamp":1718348068000},"page":"921-926","source":"Crossref","is-referenced-by-count":2,"title":["Deferral of blood donors who have ever stayed in a <i>Trypanosoma cruzi<\/i> endemic area: An international survey"],"prefix":"10.1111","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1748-4198","authenticated-orcid":false,"given":"Antoine","family":"Lewin","sequence":"first","affiliation":[{"name":"Medical Affairs and Innovation H\u00e9ma\u2010Qu\u00e9bec  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Tonnetti","sequence":"additional","affiliation":[{"name":"Scientific Affairs American Red Cross  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5685-5380","authenticated-orcid":false,"given":"Christian","family":"Renaud","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation H\u00e9ma\u2010Qu\u00e9bec  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2519-1109","authenticated-orcid":false,"given":"Steven J.","family":"Drews","sequence":"additional","affiliation":[{"name":"Canadian Blood Services, Department of Laboratory Medicine &amp; Pathology University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8181-9517","authenticated-orcid":false,"given":"Evan M.","family":"Bloch","sequence":"additional","affiliation":[{"name":"Division of Transfusion Medicine, Department of Pathology Johns Hopkins University School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Parasite and Surveillance Risk Assessment and Policy Subgroups of the ISBT Working Party on Transfusion\u2010Transmitted Infectious Diseases","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31612-4"},{"key":"e_1_2_9_3_1","first-page":"540","article-title":"Chagas disease and transfusion medicine: a perspective from non\u2010endemic countries","volume":"13","author":"Angheben A","year":"2015","journal-title":"Blood Transfus"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.5334\/gh.1150"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03554.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn424"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13164"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2009.00915.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02686.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02476.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03599.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03950.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.patbio.2007.06.008"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03569.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000446264"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03856.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/406402"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-111-10-851"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.13692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T03:09:54Z","timestamp":1728011394000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.13692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,13]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/vox.13692"],"URL":"https:\/\/doi.org\/10.1111\/vox.13692","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"value":"0042-9007","type":"print"},{"value":"1423-0410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,13]]}}}