{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:08:08Z","timestamp":1747188488310,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Postpartum anaemia is a prevalent health problem. We aimed to determine the compliance rate for red blood cell (RBC) transfusion indication among postpartum women in a single tertiary care centre in Quebec, Canada.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Retrospective cohort study including all women \u22656\u2009h postpartum who received \u22651 RBC transfusion during their delivery hospitalization between January 2005 and February 2022. We determined our centre's compliance rate by indication as compared to current society guidelines, all published after 2015 (Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis [NATA], Royal College of Obstetricians and Gynaecologists [RCOG], American College of Obstetricians and Gynecologists [ACOG]). We then explored predictors of guideline non\u2010compliance and described transfusion practices in our centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 171 women were included. Our centre's compliance rate was 79.5% (95% confidence interval [CI] 72.7\u201384.8). Predictors of guideline non\u2010compliance were maternal medical comorbidity or abnormal placentation, both limited by large CIs (odds ratio [OR] 2.26, CI 1.02\u20134.94, <jats:italic>p<\/jats:italic>\u2009=\u20090.04; OR 4.00, CI 1.31\u201312.06, <jats:italic>p<\/jats:italic>\u2009=\u20090.01, respectively). Postpartum haemorrhage was diagnosed among 68% of the cohort, mostly due to uterine atony (73.3%). Mean baseline and nadir haemoglobin were 111\u2009g\/L (\u00b118) and 62\u2009g\/L (\u00b17.7), respectively. Multiple unit initial transfusion was found in a majority of patients (63.7%). Iron therapy was administered to 51.5% of women in\u2010hospital and 81.9% received an oral iron prescription at discharge. There were no differences in primary or secondary outcomes subsequent to relevant guideline publication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our centre's compliance rate for RBC transfusion indication meets current practice guidelines. Areas for improvement include single\u2010unit initial transfusion protocols and adjuvant iron treatment. Antenatal optimization of haemoglobin and ferritin stores may limit postpartum transfusions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13702","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:28:52Z","timestamp":1719448132000},"page":"981-986","source":"Crossref","is-referenced-by-count":0,"title":["A retrospective analysis of postpartum red blood cell transfusions at a tertiary care obstetric centre"],"prefix":"10.1111","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2023-2338","authenticated-orcid":false,"given":"Ariane","family":"Lasry","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Adant","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hematology\u2010Oncology Division University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Farag","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celya","family":"Tidafi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cassandra","family":"Wareham","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandy","family":"Malick","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010\u00c8ve","family":"Roy\u2010Lacroix","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal\u2010Fetal Medicine Division University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre\u2010Aur\u00e8le","family":"Morin","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hematology\u2010Oncology Division University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine","family":"Sauv\u00e9","sequence":"additional","affiliation":[{"name":"Department of Medicine, Obstetrical and Internal Medicine Division University of Sherbrooke  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.1007\/s00277-011-1381-2"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1016\/j.ijoa.2009.05.008"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1016\/j.ijoa.2009.02.005"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.1111\/ajo.12680"},{"doi-asserted-by":"publisher","key":"e_1_2_9_6_1","DOI":"10.1111\/1471-0528.16515"},{"doi-asserted-by":"publisher","key":"e_1_2_9_7_1","DOI":"10.1016\/j.thromres.2018.03.002"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1111\/1471-0528.12531"},{"key":"e_1_2_9_9_1","article-title":"Transfusion thresholds for guiding red blood cell transfusion","volume":"12","author":"Carson JL","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"doi-asserted-by":"publisher","key":"e_1_2_9_10_1","DOI":"10.1111\/tme.12443"},{"unstructured":"RCOG.Blood transfusions in obstetrics (green\u2010top guideline no. 47).2015.https:\/\/www.rcog.org.uk\/guidance\/browse\u2010all\u2010guidance\/green\u2010top\u2010guidelines\/blood\u2010transfusions\u2010in\u2010obstetrics\u2010green\u2010top\u2010guideline\u2010no\u201047. 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