{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T03:33:43Z","timestamp":1783481623397,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T00:00:00Z","timestamp":1728777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Reproductive\u2010aged women are at an increased risk of developing iron deficiency (ID). We aimed to develop a non\u2010invasive screening tool to identify ID in women and assess the acceptability of screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design and Methods<\/jats:title><jats:p>We screened women (age 18\u201349\u2009years) in the community of Western Australia. Primary outcome: acceptability of screening, assessed by the feasibility of recruiting the required sample size (<jats:italic>n<\/jats:italic>\u2009=\u2009323). Secondary outcomes: Hand grip strength, finger prick haemoglobin concentration (Hb), prevalence of heavy menstrual bleeding (HMB), diet, pregnancy history, blood donation, symptoms of ID and history of ID or anaemia (Hb\u2009&lt;\u2009120\u2009g\/L). Those with Hb &lt;130\u2009g\/L and no history of iron therapy in the past 2\u2009years were given referrals for venous full blood count and ferritin sampling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Across 5\u2009days, we recruited 640 eligible women. Of which, 178 (28%) had HMB and 79 (12%) were anaemic. Mean age was 33.5\u2009\u00b1\u20099.2\u2009years, and mean Hb was 132.4\u2009\u00b1\u200911.9\u2009g\/L. In the past 2\u2009years: 335 (52%) were diagnosed with ID or anaemia; 322 (50%) had taken oral iron; and 210 (33%) had an intravenous iron infusion. Vegetarian diets were followed by 89 (14%); 40 (6%) were regular blood donors; 290 (45%) had a previous pregnancy.<\/jats:p><jats:p>HMB increased the risk of symptoms of ID and having prior ID\/anaemia diagnosis (67% vs. 47%) or treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.022). Hand grip strength showed a positive relationship with both Hb (adjusted <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.012, <jats:italic>p<\/jats:italic>\u2009=\u20090.004) and ferritin (adjusted <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.135, <jats:italic>p<\/jats:italic>\u2009=\u20090.005).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ID screening was well accepted by women in the community, with high recruitment rates over a short period. Future screening tool development may consider incorporating hand grip strength and HMB assessment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13750","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T02:43:28Z","timestamp":1728873808000},"page":"22-31","source":"Crossref","is-referenced-by-count":7,"title":["Community screening for iron deficiency in reproductive aged women: Lessons learnt from Australia"],"prefix":"10.1111","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5346-7673","authenticated-orcid":false,"given":"Beth","family":"MacLean","sequence":"first","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayne","family":"Lim","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jess","family":"Fuller","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riki","family":"Wylie","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judie Yeleen","family":"Joo","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annas","family":"Al\u2010Sharea","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaahnavi","family":"Cheyyur","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Ng","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijing","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mubashshira","family":"Ahmed","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cory","family":"Dugan","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toby","family":"Richards","sequence":"additional","affiliation":[{"name":"School of Medicine University of Western Australia  Perth Australia"},{"name":"School of Health, Sport and Bioscience University of East London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14948"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15432"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12292"},{"key":"e_1_2_9_5_1","volume-title":"Heavy menstrual bleeding: assessment and management. NICE guideline [NG88]","author":"National Institute for Health and Care Excellence","year":"2018"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-017-4526-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.8020"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.13928"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0149881"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2016-097372.53"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000027271"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2014.09.027"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-6576.2002.460809.x"},{"key":"e_1_2_9_14_1","unstructured":"Australian Bureau of Statistics.Regional population by age and sex. ABS. Available from:https:\/\/www.abs.gov.au\/statistics\/people\/population\/regional-population-age-and-sex\/latest-release. Last accessed 14 Apr 2024."},{"key":"e_1_2_9_15_1","unstructured":"World Health Organization.WHO global anaemia estimates 2021 edition: global anaemia estimates in women of reproductive age by pregnancy status and in children aged 6\u201359 months. Available from:\u00a0who.int\/data\/gho\/data\/themes\/topics\/anaemia_in_women_and_children. 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