{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T19:09:28Z","timestamp":1785784168222,"version":"3.56.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T00:00:00Z","timestamp":1736812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Despite screening procedures, a few blood donors confirm positive for transfusion\u2010transmissible infections and are deferred. Effective notification of laboratory results is essential to ensure that donors are advised of confirmed results and to seek medical care. Here we report results from post\u2010notification interviews of Canadian Blood Services donors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Over 17\u2009years, 2006\u20132022, all donors with confirmed positive results for hepatitis B virus (HBV), hepatitis C virus (HCV), human T\u2010cell lymphotropic virus (HTLV) and syphilis were notified by registered mail of their result and advised to see a physician. In a separate communication, all donors were later invited to participate in a scripted interview asking whether they tested positive for an infection; if yes, which one, what their reaction was, whether they consulted a physician and whether public health contacted them. Frequencies of responses were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 2654 donors with confirmed positive test results, 876 (33%) participated; 90% said they were informed of a positive test result. Of these, about a quarter did not know for which infection they were positive. Most were surprised, and some were sad or disappointed. Most saw a physician after notification (77%). About two\u2010thirds with HBV or HCV said they were contacted by public health, slightly fewer (58%) with syphilis, 27% of those with HTLV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most donors recalled being notified and were aware of their positive test, but details of the infection were sometimes not understood or recalled, and not all donors consulted a physician about the infection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.13796","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T00:08:28Z","timestamp":1736899708000},"page":"394-400","source":"Crossref","is-referenced-by-count":6,"title":["Notification of blood donors who test positive for transfusion\u2010transmissible infections"],"prefix":"10.1111","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"first","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"},{"name":"School of Epidemiology &amp; Public Health University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyuri","family":"Naicker","sequence":"additional","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"},{"name":"School of Epidemiology &amp; Public Health University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori","family":"Osmond","sequence":"additional","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3867-1072","authenticated-orcid":false,"given":"Kelly","family":"Holloway","sequence":"additional","affiliation":[{"name":"Donation and Policy Studies Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2519-1109","authenticated-orcid":false,"given":"Steven J.","family":"Drews","sequence":"additional","affiliation":[{"name":"Microbiology Canadian Blood Services  Ottawa Ontario Canada"},{"name":"Department of Laboratory Medicine &amp; Pathology, Faculty of Medicine &amp; Dentistry University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Bigham","sequence":"additional","affiliation":[{"name":"Medical Laboratory and Stem Cell Services Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9904-9952","authenticated-orcid":false,"given":"Mindy","family":"Goldman","sequence":"additional","affiliation":[{"name":"Donation and Policy Studies Canadian Blood Services  Ottawa Ontario Canada"},{"name":"Department of Pathology &amp; Laboratory Medicine University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,14]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Canadian Blood Services.Surveillance Report 2022. Available from:https:\/\/www.blood.ca\/en\/about-us\/reports-and-publications#Reports. Last accessed 10 Sep 2024."},{"key":"e_1_2_9_3_1","first-page":"1","volume-title":"Blood donor health and safety","author":"Rossman SN","year":"2022"},{"key":"e_1_2_9_4_1","unstructured":"Government of Canada.Guidance document: blood regulations. Section 42. Available from:https:\/\/www.canada.ca\/en\/health\u2010canada\/services\/drugs\u2010health\u2010products\/biologics\u2010radiopharmaceuticals\u2010genetic\u2010therapies\/applications\u2010submissions\/guidance\u2010documents\/blood\u2010regulations\/guidance\u2010document\u2010blood\u2010regulations.html#s56. Last accessed 2 Jul 2024."},{"key":"e_1_2_9_5_1","unstructured":"Canadian Standards Association.Blood and blood components Z902:20. Available from:https:\/\/www.csagroup.org\/store\/product\/2427533\/. Last accessed 10 Sep 2024."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12644"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12143"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12469"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1992.32893032092.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2004.03347.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2007.01483.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12268"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13578"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15020409"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-19790-2"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmu041"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.17269\/s41997-024-00886-6"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17393"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17878"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-020-05737-x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2893.2005.00651.x"},{"key":"e_1_2_9_22_1","unstructured":"Canadian Network on Hepatitis C.Blueprint to inform hepatitis C elimination efforts in Canada. Available from:https:\/\/www.canhepc.ca\/en\/elimination\/blueprint. Last accessed 18 Sep 2024."},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13715"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.13796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:25:31Z","timestamp":1745450731000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.13796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,14]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/vox.13796"],"URL":"https:\/\/doi.org\/10.1111\/vox.13796","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"value":"0042-9007","type":"print"},{"value":"1423-0410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,14]]}}}