{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T02:57:36Z","timestamp":1771210656914,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Seasonal vaccinations reduce donor illness and appointment cancellations and ensure plasma products have antibodies to vaccine\u2010directed strains. We aimed to describe donor influenza and COVID\u201019 vaccination history and compare this with the general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Two online donor surveys were carried out in 2021 and 2024. Donors were asked about demographics, influenza (2019\/2020, 2020\/2021 and 2023\/2024 seasons) and COVID\u201019 (ever and 2023\/2024 season) vaccination and reasons for vaccination choices. General population vaccination statistics were extracted from public reports. Percentages of donors receiving vaccination were calculated with 95% confidence intervals. Multiple logistic regression models were fitted with demographics as independent variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In survey 1, 4582 (30.4% response rate) donors completed a questionnaire; in survey 2, 6376 (21% response rate). More donors under age 65 received the influenza vaccine compared with the general population under age 65 (58% vs. 30% in 2019\/2020, 63% vs. 28% in 2023\/2024, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) and aged 65+ (81% vs. 70% in 2019\/2020, 90% vs. 73% in 2023\/2024, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Fewer donors and the general population received the COVID\u201019 vaccine in 2023\/2024 (under 65 45% vs. 39%; 65+ 76% vs. 67%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Most said they were vaccinated to prevent infection and protect others.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Seasonal vaccination rates are higher in older donors, consistent with public health recommendations. Blood donors are more likely to be vaccinated against seasonal influenza than the general population, but post\u2010pandemic uptake of the COVID\u201019 booster vaccine was low, more similar to the general population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vox.70006","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T13:42:30Z","timestamp":1741700550000},"page":"464-472","source":"Crossref","is-referenced-by-count":3,"title":["Influenza and <scp>COVID<\/scp>\u201019 vaccination in Canadian blood donors: A comparison across pre\u2010 and post\u2010pandemic periods"],"prefix":"10.1111","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"first","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"},{"name":"School of Epidemiology &amp; Public Health University of Ottawa  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori","family":"Osmond","sequence":"additional","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9904-9952","authenticated-orcid":false,"given":"Mindy","family":"Goldman","sequence":"additional","affiliation":[{"name":"Donation and Policy Studies Canadian Blood Services  Ottawa Ontario Canada"},{"name":"Department of Pathology &amp; Laboratory Medicine University of Ottawa  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2519-1109","authenticated-orcid":false,"given":"Steven J.","family":"Drews","sequence":"additional","affiliation":[{"name":"Microbiology Canadian Blood Services  Edmonton Alberta Canada"},{"name":"Department of Laboratory Medicine &amp; Pathology, Faculty of Medicine &amp; Dentistry University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvacx.2024.100498"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiab514"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2022.08.002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00123-24"},{"key":"e_1_2_9_6_1","unstructured":"World Health Organization.Statement on the antigen composition of COVID\u201019 vaccine. 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Last accessed 25 Nov 2024."},{"key":"e_1_2_9_20_1","unstructured":"Public Health Agency of Canada.COVID\u201019 vaccination coverage survey (CVCS): cycle 2 full report. Available from:https:\/\/www.canada.ca\/en\/public\u2010health\/services\/publications\/vaccines\u2010immunization\/covid\u201019\u2010vaccination\u2010coverage\u2010survey\/full\u2010report\u2010cycle\u20102.html. Last accessed 25 Nov 2024"},{"key":"e_1_2_9_21_1","unstructured":"Public Health Agency of Canada.Highlights of the 2019\u20132020 seasonal influenza (flu) vaccination coverage survey. Available from:https:\/\/www.canada.ca\/en\/public\u2010health\/services\/immunization\u2010vaccines\/vaccination\u2010coverage\/2019\u20102020\u2010seasonal\u2010influenza\u2010flu\u2010vaccine\u2010coverage.html. Last accessed 25 Nov 2024."},{"key":"e_1_2_9_22_1","unstructured":"Public Health Agency of Canada.Highlights of the 2020\u20132021 seasonal influenza (flu) vaccination coverage survey. 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