{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:21:35Z","timestamp":1765412495310,"version":"3.46.0"},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Hepatitis delta virus (HDV) superinfection with hepatitis B virus (HBV) infection can cause a severe form of viral hepatitis. A nation\u2010wide general population study in Cameroon in 2018 showed a high seroprevalence of 46.7% (901\/1928) of HDV among hepatitis B surface antigen (HBsAg) carriers. However, there is a lack of published data on the seroprevalence of HDV among the HBV\u2010positive blood donor population in Cameroon. The aim of this study was to determine the seroprevalence of HDV among blood donors positive for HBV at the Yaounde Central Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>First\u2010time blood donors were screened for HBsAg between June and November 2022 using a rapid test (DIASPOT), followed by an enzyme\u2010linked immunosorbent assay (ELISA) (Fortress diagnostics) if the rapid test was negative. HBsAg\u2010positive samples were further screened for anti\u2010HDV by ELISA (HDVAb, DIAPRO, DAB.CE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 195 blood donors who tested positive for HBsAg, 91 (46.7%) were positive by the rapid test, whereas 104 (53.3%) were negative by the rapid test but positive by ELISA. Anti\u2010HDV was detected in 39 (20%) of samples. Anti\u2010HDV reactivity was associated with the HBsAg screening method (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The burden of HDV\/HBV infection among asymptomatic blood donors in the Yaounde region of Cameroon is of concern.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70123","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:39:41Z","timestamp":1760575181000},"page":"1268-1272","source":"Crossref","is-referenced-by-count":0,"title":["Seroprevalence of hepatitis D virus among blood donors with hepatitis B surface antigen at Yaounde Central Hospital, Cameroon"],"prefix":"10.1111","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6513-8358","authenticated-orcid":false,"given":"Hortense Ngegni","family":"Pangetna","sequence":"first","affiliation":[{"name":"Blood Bank Central Hospital of Yaounde  Yaounde Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Symphorien","family":"Ewodo","sequence":"additional","affiliation":[{"name":"National Blood Center of Cameroon  Yaounde Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Vermeulen","sequence":"additional","affiliation":[{"name":"South African National Blood Service  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Custer","sequence":"additional","affiliation":[{"name":"Epidemiology and Policy Science Department Vitalant Research Institute  San Francisco California USA"},{"name":"Department of Laboratory Medicine University of California San Francisco  San Franciso California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques Delors Toumansie","family":"Mfonkou","sequence":"additional","affiliation":[{"name":"Laboratory of Virology Centre Pasteur du Cameroun  Yaounde Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Ebogo","sequence":"additional","affiliation":[{"name":"Center for Research on Health and Priority Pathologies Institute of Medical Research and Medicinal Plants Studies  Yaounde Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micheline","family":"Mimche","sequence":"additional","affiliation":[{"name":"Blood Bank Central Hospital of Yaounde  Yaounde Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Njouom","sequence":"additional","affiliation":[{"name":"Laboratory of Virology Centre Pasteur du Cameroun  Yaounde Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"volume-title":"Global hepatitis report 2017","year":"2017","author":"World Health Organization","key":"e_1_2_9_2_1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.04.008"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(17)30298-X"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2017.05.010"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-019-4460-4"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-30078-5"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-022-05976-7"},{"key":"e_1_2_9_9_1","article-title":"Pr\u00e9valence des infections transmissibles par transfusion sanguine chez les donneurs de Sang \u00e0 l'H\u00f4pital Central de Yaound\u00e9 \u2013 Cameroun","volume":"20","author":"Fohoue AM","year":"2019","journal-title":"Health Sci Dis"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12157-015-0646-4"},{"key":"e_1_2_9_11_1","unstructured":"ZeyeMMJ ZeyeJ DiagbougaS DjigmaF SanouM Obiri\u2010YeboahD et al.Prevalence of hepatitis virus delta infection among HBVAgs positive blood donors at the regional blood transfusion Center of Ouagadougou Burkina Faso Action Preventive Health Association\/Center for information and screening on immunization.2017;5:1\u20136."},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.992817"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.70123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:18:24Z","timestamp":1765412304000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.70123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,15]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/vox.70123"],"URL":"https:\/\/doi.org\/10.1111\/vox.70123","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"type":"print","value":"0042-9007"},{"type":"electronic","value":"1423-0410"}],"subject":[],"published":{"date-parts":[[2025,10,15]]}}}