{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T14:42:02Z","timestamp":1790347322224,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL\u2010960569"],"award-info":[{"award-number":["OLL\u2010960569"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>\n                      The Nordic region includes Denmark, Finland, Iceland, Norway and Sweden, with a population of &gt;27.5 million. Blood services are managed differently in each country. Current data on platelet concentrate (\n                      <jats:styled-content style=\"fixed-case\">PC<\/jats:styled-content>\n                      ) production methods and capacity are important for developing efficiency and cross\u2010border preparedness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      Retrospective data for 2018\u20132022 were collected through an online survey sent to all blood centres producing platelets in the region. Questions focused on collection procedures (aphaeresis [\n                      <jats:styled-content style=\"fixed-case\">AP<\/jats:styled-content>\n                      ] or whole blood [\n                      <jats:styled-content style=\"fixed-case\">WB<\/jats:styled-content>\n                      ]\u2010derived pools), use of bacterial culture screening (\n                      <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content>\n                      ) or pathogen reduction (\n                      <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>\n                      ), shelf\u2010life, transfusion practices and quality control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 43 blood centres provided data (83% response), including complete national coverage for Sweden, Finland and Iceland. Between 2018 and 2022, 632,596\n                      <jats:styled-content style=\"fixed-case\">PCs<\/jats:styled-content>\n                      were produced at participating centres. Annual\n                      <jats:styled-content style=\"fixed-case\">PC<\/jats:styled-content>\n                      production was stable over the period. Most\n                      <jats:styled-content style=\"fixed-case\">PCs<\/jats:styled-content>\n                      were\n                      <jats:styled-content style=\"fixed-case\">WB<\/jats:styled-content>\n                      pools (77%). Automated separation to produce interim platelet unit (\n                      <jats:styled-content style=\"fixed-case\">IPU<\/jats:styled-content>\n                      ) pools was performed at 19 centres.\n                      <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content>\n                      were used in 17 and 23 centres, respectively. Shelf\u2010life ranged from 5\u2009days (no safety measure) to 7\u2009days (\n                      <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>\n                      or\n                      <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content>\n                      ). The number of\n                      <jats:styled-content style=\"fixed-case\">PCs<\/jats:styled-content>\n                      transfused in the region declined by ~5% from 2018 to 2022.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Platelet production methods, including safety measures to prevent bacterial contamination, varied widely in the Nordic region. Harmonization, including the use of\n                      <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>\n                      or\n                      <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content>\n                      with 7\u2010day storage, may contribute to resilient platelet supplies in the region.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70163","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T01:59:14Z","timestamp":1764899954000},"page":"237-244","source":"Crossref","is-referenced-by-count":1,"title":["Practices in platelet production: A Nordic perspective (2018\u20132022)"],"prefix":"10.1111","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6791-6908","authenticated-orcid":false,"given":"Aseel","family":"Alshamari","sequence":"first","affiliation":[{"name":"Department of Clinical Immunology and Transfusion Medicine, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tynng\u00e5rd","family":"Nahreen","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Clinical Sciences Link\u00f6ping University  Link\u00f6ping Sweden"},{"name":"Healthcare Research Strategy Department Region \u00d6sterg\u00f6tland  Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarkko","family":"Ihalainen","sequence":"additional","affiliation":[{"name":"Finnish Red Cross Blood Service  Vantaa Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"Hemminki","sequence":"additional","affiliation":[{"name":"Finnish Red Cross Blood Service  Vantaa Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ragna","family":"Landr\u00f6","sequence":"additional","affiliation":[{"name":"The Blood Bank, Landspitali  Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erna","family":"Kn\u00fatsd\u00f3ttir","sequence":"additional","affiliation":[{"name":"The Blood Bank, Landspitali  Reykjavik Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betina","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1689-7628","authenticated-orcid":false,"given":"Elena","family":"Danilova","sequence":"additional","affiliation":[{"name":"Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbora","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Immunology and Transfusion Medicine St. Olavs Hospital  Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8674-0784","authenticated-orcid":false,"given":"Marja\u2010Kaisa","family":"Auvinen","sequence":"additional","affiliation":[{"name":"Transfusion Medicine Uppsala University Hospital  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Ramstr\u00f6m","sequence":"additional","affiliation":[{"name":"School of Medical Sciences, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad R.","family":"Abedi","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology and Transfusion Medicine Unilabs Laboratory Diagnostic Services  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"European Commission.Summary of the 2023 (2022 data) annual reporting of serious adverse reactions and events for blood and blood components. 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