{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:38:02Z","timestamp":1789231082854,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Vasovagal reactions (VVRs) are common adverse events associated with blood donation. While previous research has focused on intrinsic donor\u2010related risk factors, we previously identified an association between specific meteorological elements and VVR incidence. This study aims to build on our earlier findings by investigating the potential modifying effects of collection setting and donation type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design and Methods<\/jats:title>\n                    <jats:p>This study analysed VVR incidence data from blood donations collected in northern Nara Prefecture, Japan, over a 3\u2010year period (April 2020\u2013March 2023). Daily VVR incidence rates were calculated and analysed in relation to meteorological elements, including temperature, humidity, atmospheric pressure and other related factors. Comparisons across quartiles of meteorological values were performed using Kruskal\u2013Wallis and Jonckheere\u2013Terpstra tests. Subgroup analyses were conducted by collection setting and donation type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In mobile collections (whole blood only), significant associations were found only with the 7\u2010day weighted moving average (7d WMA) of temperature and precipitation. In fixed\u2010site collections, several temperature\u2010related elements were significantly associated with VVR incidence in both same\u2010day and 7d WMA analyses. Further stratification showed that whole blood donations at fixed sites showed limited associations with meteorological elements, whereas apheresis donations showed significant relationships with multiple temperature\u2010related parameters in both same\u2010day and 7d WMA analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Meteorological elements affecting VVR incidence vary by the collection setting and donation type. Apheresis donations appear to be susceptible to environmental influences, especially ambient temperature. These findings highlight the importance of incorporating meteorological considerations into donor safety measures and operational planning, particularly for apheresis collections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70204","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T02:33:31Z","timestamp":1770690811000},"page":"562-569","source":"Crossref","is-referenced-by-count":1,"title":["Meteorological elements associated with vasovagal reactions in blood donors: Influence of collection setting and donation type"],"prefix":"10.1111","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9358-6141","authenticated-orcid":false,"given":"Satohiro","family":"Nakagawa","sequence":"first","affiliation":[{"name":"Japanese Red Cross Nara Blood Center  Yamatokoriyama Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Shima","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Nara Blood Center  Yamatokoriyama Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6030-5207","authenticated-orcid":false,"given":"Toshiya","family":"Nishikubo","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Nara Blood Center  Yamatokoriyama Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1773-5535","authenticated-orcid":false,"given":"Yoshihiko","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Nara Blood Center  Yamatokoriyama Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vox.13048"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2015.01.009"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03202.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03551.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12488"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18078"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4330\/wjc.v14.i3.152"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.11154\/pain.36.75"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2024.04.001"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3925\/jjtc.71.532"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cppeds.2013.12.014"},{"key":"e_1_2_9_13_1","volume-title":"Immunization stress\u2010related response: a manual for program managers and health professionals to prevent, identify and respond to stress\u2010related responses following immunization","author":"Pharmacovigilance","year":"2019"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3925\/jjtc.70.452"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/voxs.12540"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eul095"},{"key":"e_1_2_9_17_1","first-page":"21","article-title":"Prevention of venous return decrease reduces vasovagal reaction in blood donors","volume":"38","author":"Higa Y","year":"2015","journal-title":"J Soc Jpn Blood 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