{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:30:24Z","timestamp":1790425824063,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Pre\u2010donation deferral can negatively affect donor retention and blood supply sustainability. Comprehensive analysis of national deferral rates and reasons can inform evidence\u2010based adjustments to donor eligibility criteria and improve the specificity of pre\u2010donation screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Data on deferral rates and the top three deferral causes were collected from 47 blood establishments (BEs) (23 provincial\u2010level, 24 prefectural\u2010level) across China between 2016 and 2024. Deferral reasons were classified into 16 standardized categories. Chi\u2010square and Spearman correlation analyses were performed to examine differences between groups and associations with potential influencing factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 42.6 million whole blood (WB) and 5.9 million apheresis platelet (AP) donation attempts were analysed. Overall deferral rates were 11.4% for WB and 14.7% for AP donations, with provincial\u2010level BEs exhibiting higher rates than prefectural\u2010level BEs, for both donation types. The most frequently reported deferral reasons were elevated alanine aminotransferase (ALT) levels, low haemoglobin (Hb), lipaemia and abnormal blood pressure. Deferral rates were positively associated with the proportion of first\u2010time donors and, for WB donors, with the detection rate of hepatitis B surface antigen (HBsAg).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pre\u2010donation deferral remains relatively high in China, with elevated ALT, low Hb, lipaemia and abnormal blood pressure identified as the most frequent causes. These findings highlight the need for evidence\u2010based revisions of eligibility criteria, targeted donor education and strategies to promote repeat donation. Standardizing pre\u2010donation screening practices across BEs may reduce unnecessary deferrals, enhance donor retention and support a more efficient and sustainable blood supply.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70246","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T01:50:41Z","timestamp":1773885041000},"page":"927-935","source":"Crossref","is-referenced-by-count":1,"title":["Pre\u2010donation deferral rates and causes among whole blood and apheresis platelet donors in China: A multi\u2010centre retrospective study (2016\u20132024)"],"prefix":"10.1111","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0054-4924","authenticated-orcid":false,"given":"Yuan","family":"Zhang","sequence":"first","affiliation":[{"name":"Shaanxi Blood Center  Xian Shaanxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojun","family":"Wei","sequence":"additional","affiliation":[{"name":"Guangxi Blood 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