{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T14:57:58Z","timestamp":1791644278858,"version":"4.3.4"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>\n                      Chagas disease (\n                      <jats:italic>Trypanosoma cruzi<\/jats:italic>\n                      ), prevalent in Mexico, Central and South America, can be transfusion\u2010transmitted. Selective serological testing of blood donors was implemented over 15\u2009years ago. We describe the trends in infections and characteristics of donors selected for testing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Donor selection for testing was based on birth in Latin America and\/or mother\/grandmother born in Latin America and\/or travel to Latin America (30\u2009days duration at H\u00e9ma\u2010Qu\u00e9bec [HQ], 6\u2009months at Canadian Blood Services [CBS]). All first\u2010time donors (2010\u20132024) were analysed. Frequencies were compiled by gender, age group, region and residential material deprivation and ethnocultural composition indices. Multiple logistic regression compared donors with risk factors (tested) versus those without risk factors (not tested).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 67,490 tested donors, most were born in Mexico, Central or South America (71% at CBS). Of the 27 donors positive for\n                      <jats:italic>T. cruzi<\/jats:italic>\n                      antibodies, more were from Ontario, materially deprived and ethnocultural concentrated neighbourhoods. One had mother\/grandmother birth, but none had travel as the sole risk factor. Tested donors were similar to non\u2010tested donors except more likely to be aged 30\u201349 (odds ratio [OR] 1.4, 1.37\u20131.44 CBS, 1.57, 1.51\u20131.63 HQ) and live in more ethnoculturally concentrated neighbourhoods (OR 2.09, 2.01\u20132.18 CBS, 3.46, 3.29\u20133.64 HQ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Birth in Latin America captures most\n                      <jats:italic>T. cruzi<\/jats:italic>\n                      antibody positive donations. Mother\/grandmother risk occasionally yields a positive donation, but travel history does not. Infections in donors are rare, but selective testing interdicts a small risk of\n                      <jats:italic>T. cruzi<\/jats:italic>\n                      positive blood products being released into inventory.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70299","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T03:11:15Z","timestamp":1780369875000},"page":"1347-1355","source":"Crossref","is-referenced-by-count":1,"title":["Chagas disease in Canadian blood donors: 15\u2009years of selective testing"],"prefix":"10.1111","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5332-2789","authenticated-orcid":false,"given":"Sheila F.","family":"O'Brien","sequence":"first","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"},{"name":"School of Epidemiology &amp; Public Health University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9904-9952","authenticated-orcid":false,"given":"Mindy","family":"Goldman","sequence":"additional","affiliation":[{"name":"Donation and Policy Studies Canadian Blood Services  Ottawa Ontario Canada"},{"name":"Department of Pathology &amp; Laboratory Medicine University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1748-4198","authenticated-orcid":false,"given":"Antoine","family":"Lewin","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation, H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Department of Mathematics, Faculty of Science University of Sherbrooke  Sherbrooke Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samra","family":"Uzicanin","sequence":"additional","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenli","family":"Fan","sequence":"additional","affiliation":[{"name":"Epidemiology &amp; Surveillance Canadian Blood Services  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Drews","sequence":"additional","affiliation":[{"name":"Microbiology Canadian Blood Services  Edmonton Alberta Canada"},{"name":"Department of Laboratory Medicine &amp; Pathology, Faculty of Medicine &amp; Dentistry University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2024.100881"},{"key":"e_1_2_9_3_1","unstructured":"World Health Organization.Chagas disease (also known as American trypanosomiasis). 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