{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:18:57Z","timestamp":1789165137207,"version":"build-2803163510"},"reference-count":85,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Social movements in favour of greater diversity, equity and inclusion have led societies to re\u2010examine the concepts of sex assigned at birth and gender identity. These have also impacted healthcare systems and blood operators. Gender identities extending beyond the concept of cisgender binary individuals might have an impact on the safety of blood components for recipients, and on the safety of the donation process itself. Furthermore, the procedures put in place by blood operators to welcome donors from sexual and gender diversity might have a major impact on donors' psychological well\u2010being and retention. This review provides an overview of the processes used by blood operators to mitigate potential health risks for both donors and recipients associated with trans and non\u2010binary donors. It also examines how blood operators address sexual and gender diversity in the donor registration process. Regarding the theoretical risks of human immunodeficiency virus (HIV) transmission and of transfusion\u2010related acute lung injury arising from trans donors, the available evidence suggests that the hypothetical increases would be negligible. Recent studies show that adapting the donor history questionnaire for sexual and gender diversity is still an ongoing process. Improvements are needed, especially in communication with stakeholders, staff training and reducing health risks for donors. The broadening of sexual and gender identities provides an opportunity for blood operators to act as agents of positive social change towards greater safety, diversity, equity and inclusion in our societies.<\/jats:p>","DOI":"10.1111\/vox.70301","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T01:46:22Z","timestamp":1780623982000},"page":"1275-1289","source":"Crossref","is-referenced-by-count":0,"title":["Blood donor safety and selection criteria for individuals self\u2010identifying as trans or non\u2010binary"],"prefix":"10.1111","volume":"121","author":[{"given":"Jean\u2010Fran\u00e7ois","family":"Leblanc","sequence":"first","affiliation":[{"name":"Medical Affairs and Innovation H\u00e9ma\u2010Qu\u00e9bec  Qu\u00e9bec City Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Thibeault","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5685-5380","authenticated-orcid":false,"given":"Christian","family":"Renaud","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1748-4198","authenticated-orcid":false,"given":"Antoine","family":"Lewin","sequence":"additional","affiliation":[{"name":"Medical Affairs and Innovation H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Center for Biologics Evaluation and Research Food and Drug Administration U.S. Department of Health and Human Services.Recommendations for evaluating donor eligibility using individual risk\u2010based questions to reduce the risk of human immunodeficiency virus transmission by blood and blood products; Guidance for industry2023. 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