{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T02:03:25Z","timestamp":1784599405997,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["75N92019D00038"],"award-info":[{"award-number":["75N92019D00038"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>In 2020, Brazil implemented individual donor assessment (IDA), expanding eligibility to include individuals previously deferred, such as men who have sex with men (MSM). We assessed human immunodeficiency virus (HIV) incidence and correlates of incident infection among blood donors following this policy change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>We analysed donation data from five Brazilian blood centres from 2020 to 2024. Routine HIV screening included fourth\u2010generation antigen\/antibody (Ag\/Ab) assays and nucleic acid testing (NAT). Additional testing (limiting antigen [LAg] avidity, viral load) was used to identify recent infections. Incidence was estimated separately for first\u2010time donors (FTD) and repeat donors (RD), and multivariable Poisson regression was used to assess correlates of incident infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 1.66 million screened donations, 2598 (0.16%) were HIV\u2010reactive on routine screening. Residual serum was available for 74% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091927), and following additional testing, 98 were classified as recent HIV infections. HIV incidence was higher among FTD (20.9\/100,000 person\u2010years) than RD (18.3\/100,000). Higher incidence was observed among male and younger donors as well as those identifying as Black or multiracial (\n                      <jats:italic>Pardo<\/jats:italic>\n                      ). Incidence varied between blood centres, with overall incidence stable across the study period. No increase in the residual risk (RR) of HIV transfusion\u2010transmission was observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings indicate that the adoption of IDA in Brazil did not change blood safety. HIV incidence remained stable, with varying HIV infection patterns reflecting known disparities in the epidemiology of HIV in Brazil.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70329","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T01:23:00Z","timestamp":1784596980000},"source":"Crossref","is-referenced-by-count":0,"title":["<scp>HIV<\/scp>\n                    incidence and correlates of incident infection among Brazilian blood donors following adoption of individual donor assessment"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3217-5898","authenticated-orcid":false,"given":"Renata","family":"Buccheri","sequence":"first","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7046-7245","authenticated-orcid":false,"given":"Eduard","family":"Grebe","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"},{"name":"School of Public Health University of Cape Town  Cape Town South\u00a0Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7844-7821","authenticated-orcid":false,"given":"Donald E.","family":"Warden","sequence":"additional","affiliation":[{"name":"Westat  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Miranda","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais  Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ligia","family":"Capuani","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo S\u00e2o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia S.","family":"Alencar","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Medicina Laboratorial LIM 03\u2013HCFMUSP  S\u00e3o Paulo S\u00e2o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz","family":"Amorim","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemominas  Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar","family":"de Almeida\u2010Neto","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Pro\u2010Sangue Hemocentro de S\u00e3o Paulo  S\u00e2o Paulo S\u00e2o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maisa","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemorio  Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Loureiro","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemope  Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Fraiji","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Hemoam  Manaus Amazonas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Di Germanio","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leilani","family":"Montalvo","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Leddy","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mars","family":"Stone","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2623-5126","authenticated-orcid":false,"given":"Ester C.","family":"Sabino","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-366X","authenticated-orcid":false,"given":"Brian","family":"Custer","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"},{"name":"Department of Laboratory Medicine, University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Recipient Epidemiology and Donor Evaluation Study\u2010IV\u2010Pediatric (REDS\u2010IV\u2010P)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.transci.2022.103578","article-title":"Perceptions and practices of the Brazilian LGBT+ population toward blood donation","volume":"62","author":"Martinez EZ","year":"2023","journal-title":"Transfus Apher Sci"},{"key":"e_1_2_9_3_1","unstructured":"Ag\u00eancia Nacional de Vigil\u00e2ncia Sanit\u00e1ria.Guia para inclus\u00e3o de crit\u00e9rios na triagem cl\u00ednica e epidemiol\u00f3gica de candidatos a doa\u00e7\u00e3o de sangue baseados em pr\u00e1ticas individuais acrescidas de risco para infec\u00e7\u00f5es transmiss\u00edveis pelo sangue.2020. 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