{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:34:18Z","timestamp":1787016858788,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Research on donor complications has focused mainly on vasovagal reactions, with less attention to local complications. Early detection of upper\u2010extremity deep vein thrombosis (UDVT) is essential to prevent serious outcomes such as pulmonary embolism. This study assesses the association between UDVT and blood donation to facilitate identification and improve donor care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A literature search was conducted using PubMed and Notify Library. Reports on therapeutic apheresis and clinical studies were excluded. Articles reporting aggregated data or individual cases of venous thrombosis, thrombophlebitis or phlebitis after donation of blood or components of blood were selected. Furthermore, donor records suggestive of arm thrombosis from December 2022 to January 2025 were extracted from our blood bank database. Donors were interviewed by telephone with a standardized questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A literature search yielded 7 reports presenting 9 cases of UDVT, as well as a conference summary describing 20 cases. Arm pain and swelling were common symptoms, typically occurring within hours to days after donation. Risk factors for thrombosis were repeated sport\u2010related arm movements, complicated phlebotomy, smoking, oral contraceptive use and genetic mutations. In our blood bank, 12 donors reported symptoms suggestive of venous thrombosis. Based on information collected in the interviews, there were three cases of UDVT, four cases of thrombophlebitis, two cases of phlebitis, one finger infection, one leg deep vein thrombosis (DVT) and one haematoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>UDVT is a rare complication that can occur days after donation. Prompt evaluation and referral to a general practitioner will contribute to preventing harmful consequences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70349","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:58Z","timestamp":1787015578000},"source":"Crossref","is-referenced-by-count":0,"title":["Identification of thrombotic complications of the arm in blood donors: Evidence from literature and national data"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1791-6421","authenticated-orcid":false,"given":"Niubel D\u00edaz","family":"Padilla","sequence":"first","affiliation":[{"name":"Department of Donor Medicine, Department of Medical Affairs Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armand","family":"Snel","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine, Department of Medical Affairs Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mardin","family":"Rashid","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine, Department of Medical Affairs Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Bank","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Department of Medical Affairs Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3451-9911","authenticated-orcid":false,"given":"Johanna","family":"Wiersum\u2010Osselton","sequence":"additional","affiliation":[{"name":"Department of Donor Medicine, Department of Medical Affairs Sanquin Blood Supply Foundation  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1111\/trf.16333","article-title":"Frequency of rare, serious donor reactions: international perspective","volume":"61","author":"Young P","year":"2021","journal-title":"Transfusion"},{"key":"e_1_2_9_3_1","volume-title":"Standard for surveillance of complications related to blood donation","author":"Goldman M","year":"2014"},{"key":"e_1_2_9_4_1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/trf.18078","article-title":"Risk factors for vasovagal reactions in blood donors: a systematic review and meta\u2010analysis","volume":"65","author":"Wu Y","year":"2025","journal-title":"Transfusion"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1159\/000364849","article-title":"Management of young blood 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