{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T23:09:05Z","timestamp":1788736145347,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T00:00:00Z","timestamp":1788652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T00:00:00Z","timestamp":1788652800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vox Sanguinis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Platelet concentrates (PCs) are difficult to manage because of their short shelf\u2010life and variable clinical demand. The aim of this study was to evaluate the impact of a modified platelet inventory management strategy at a Regional Blood Donation and Treatment Center on product utilization and expiration\u2010related losses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This retrospective observational study analyzed platelet inventory management from 2015 to 2025, focusing on changes introduced in 2024. The strategy included an Excel\u2010based decision\u2010support tool incorporating current inventory, predefined target stock levels, ABO distribution, and the use of group AB platelets as universal products. Apheresis platelet collection was also reorganized to improve supply flexibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Between 2015 and 2025, the number of transfused PCs increased from 8306 to 13,971\u2009units\/year (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), while the outdate rate decreased from 1.86% to 0.04% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0009). After 2023, apheresis platelets accounted for over 40% of issued products, and the mean use of group AB platelets increased from approximately 7% to over 12%. The mean age of transfused platelets increased from 2.38\u2009\u00b1\u20091.19\u2009days in 2015\u20132023 to 2.62\u2009\u00b1\u20091.33\u2009days in 2024\u20132025.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Implementation of an integrated platelet inventory management strategy improved inventory utilization, substantially reduced expiration\u2010related losses, and maintained supply despite increasing clinical demand. Simple decision\u2010support tools combined with organizational changes may provide a practical approach to platelet inventory optimization in regional blood centers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vox.70366","type":"journal-article","created":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T22:56:22Z","timestamp":1788735382000},"source":"Crossref","is-referenced-by-count":0,"title":["Optimization of platelet concentrate inventory management using a simple standardized decision\u2010support model: A retrospective study from a Regional Blood Center"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2945-188X","authenticated-orcid":false,"given":"Anna","family":"Lizo\u0144","sequence":"first","affiliation":[{"name":"Department of Medical Diagnostics, Faculty of Pharmacy Jagiellonian University Medical College  Krak\u00f3w Poland"},{"name":"Regional Blood Donation and Treatment Center  Krak\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Marsza\u0142ek","sequence":"additional","affiliation":[{"name":"Regional Blood Donation and Treatment Center  Krak\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0452-295X","authenticated-orcid":false,"given":"Wirginia","family":"Krzy\u015bciak","sequence":"additional","affiliation":[{"name":"Department of Medical Diagnostics, Faculty of Pharmacy Jagiellonian University Medical College  Krak\u00f3w Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1111\/poms.13009","article-title":"Joint decisions for blood collection and platelet inventory control","volume":"28","author":"Chen S","year":"2019","journal-title":"Prod Oper Manag"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.ejor.2023.03.007","article-title":"Supporting platelet inventory management decisions: what is the effect of extending platelets' shelf life?","volume":"310","author":"Dillon M","year":"2023","journal-title":"Eur J Oper Res"},{"key":"e_1_2_9_4_1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.tmrv.2019.08.006","article-title":"Is platelet expiring out of date? A systematic review","volume":"34","author":"Flint AW","year":"2020","journal-title":"Transfus Med Rev"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1111\/trf.13081","article-title":"Implementation of a novel real\u2010time platelet inventory management system at a multi\u2010site transfusion service","volume":"55","author":"Gomez AT","year":"2015","journal-title":"Transfusion"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.tre.2025.104629","article-title":"Platelet inventory management in hospital networks: a reinforcement learning approach","volume":"208","author":"Valizadeh S","year":"2026","journal-title":"Transp Res E Logist Transp Rev"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/vox.12837","article-title":"Optimal collecting policy for apheresis platelets in a regional blood center","volume":"115","author":"Lin SW","year":"2020","journal-title":"Vox Sang"},{"key":"e_1_2_9_8_1","first-page":"95","article-title":"Platelet inventory management program: development and practical experience","volume":"41","author":"Lee HJ","year":"2020","journal-title":"Ann Lab Med"},{"key":"e_1_2_9_9_1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.56875\/2589-0646.1041","article-title":"Platelet inventory and using out\u2010of\u2010group platelet suspension: a cost\u2010effective strategy for a blood transfusion service","volume":"16","author":"Y\u0131ld\u0131z A","year":"2023","journal-title":"Hematol Oncol Stem Cell Ther"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1111\/j.1537-2995.2006.00832.x","article-title":"Variation of platelet production and discard rates in 17 blood centers representing 10 European countries from 2000 to 2002","volume":"46","author":"Veihola M","year":"2006","journal-title":"Transfusion"},{"key":"e_1_2_9_11_1","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1111\/j.1537-2995.2011.03190.x","article-title":"Platelet pool inventory management: theory meets practice","volume":"51","author":"Kort W","year":"2011","journal-title":"Transfusion"},{"key":"e_1_2_9_12_1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1537-2995.2008.01996.x","article-title":"Blood platelet production: a novel approach for practical optimization","volume":"49","author":"Van Dijk N","year":"2009","journal-title":"Transfusion"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s10729-025-09706-w","article-title":"Blood platelet inventory management: incorporating data\u2010driven demand forecasts","volume":"28","author":"Motamedi M","year":"2025","journal-title":"Health Care Manag Sci"},{"key":"e_1_2_9_14_1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/vox.13609","article-title":"Routine results of an algorithm for managing the production of blood components","volume":"119","author":"P\u00e9rez\u2010Aliaga AI","year":"2024","journal-title":"Vox Sang"},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1182\/hematology.2020000135","article-title":"Does ABO and RhD matching matter for platelet transfusion?","volume":"1","author":"Dunbar NM","year":"2020","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"e_1_2_9_16_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.tmrv.2014.11.004","article-title":"Guidance on platelet transfusion for patients with hypoproliferative thrombocytopenia","volume":"29","author":"Nahirniak S","year":"2015","journal-title":"Transfus Med Rev"},{"key":"e_1_2_9_17_1","volume-title":"Guide to the preparation, use and quality assurance of blood components","author":"European Directorate for the Quality of Medicines & HealthCare (EDQM), Council of Europe","year":"2023"},{"key":"e_1_2_9_18_1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/vox.13129","article-title":"International forum on policies and practice for transfusion of ABO and RhD non\u2010identical platelets: summary","volume":"117","author":"Cardigan R","year":"2022","journal-title":"Vox Sang"},{"key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/vox.12433","article-title":"Implications of a switch to a 100% apheresis platelet supply for patients and for blood donors: a risk benefit analysis","volume":"111","author":"Thiele T","year":"2016","journal-title":"Vox Sang"},{"key":"e_1_2_9_20_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.transci.2025.104086","article-title":"The 2024 international survey of platelet products and practice","volume":"64","author":"Ohto H","year":"2025","journal-title":"Transfus Apher Sci"},{"key":"e_1_2_9_21_1","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1111\/j.1537-2995.2008.01731.x","article-title":"Comparing the efficacy and safety of apheresis and whole blood\u2010derived platelet transfusions: a systematic review","volume":"48","author":"Heddle NM","year":"2008","journal-title":"Transfusion"},{"key":"e_1_2_9_22_1","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens11020142","article-title":"Pathogen reduction for platelets\u2014a review of recent implementation strategies","volume":"11","author":"Rebulla P","year":"2022","journal-title":"Pathogens"},{"key":"e_1_2_9_23_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/vox.12860","article-title":"Impact of implementing pathogen reduction technologies for platelets on reducing outdates","volume":"115","author":"Gorria C","year":"2020","journal-title":"Vox Sang"},{"key":"e_1_2_9_24_1","first-page":"137","article-title":"Cryopreserved platelets and amotosalen\u2010treated plasma in an experimental clot formation set\u2010up","volume":"21","author":"Sandgren P","year":"2023","journal-title":"Blood Transfus"}],"container-title":["Vox Sanguinis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.70366","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vox.70366","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vox.70366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T22:56:26Z","timestamp":1788735386000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vox.70366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,6]]},"references-count":23,"alternative-id":["10.1111\/vox.70366"],"URL":"https:\/\/doi.org\/10.1111\/vox.70366","archive":["Portico"],"relation":{},"ISSN":["0042-9007","1423-0410"],"issn-type":[{"value":"0042-9007","type":"print"},{"value":"1423-0410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,6]]},"article-number":"vox.70366"}}