{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:11:36Z","timestamp":1776132696256,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Universal Imaging Inc. 299 Adams St. Bedford Hills, NY 10507, U.S.A."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p>Canine gastrointestinal stromal tumors (GISTs) are a recent subtype of gastrointestinal spindle cell tumor recognized with the increasing use of immunohistochemistry. To our knowledge, no imaging features have been described in immunistochemically confirmed canine GISTs. The objective of this retrospective, cross\u2010sectional study was to describe ultrasonographic features of canine GISTs compared with other spindle cell tumors. Thirty\u2010seven dogs with an ultrasonographically visible gastrointestinal mass and a histopathologic diagnosis of spindle cell neoplasia were examined. Immunohistochemistry staining was performed for retrieved tissue samples to further differentiate the tumor type and each sample was interpreted by a single veterinary pathologist. Ultrasonographic features recorded examined included mass echogenicity, homogeneity, presence of cavitation, layer of origin, bowel wall symmetry, and loss of wall layering, location, size, vascularity, and evidence of perforation or ulceration. Tumor types included 19 GISTs, eight leiomyosarcomas, six leiomyomas, and four nonspecified sarcomas. Gastrointestinal stromal tumors were significantly more likely to be associated (<jats:italic>P<\/jats:italic>&lt; 0.03) with abdominal effusion than other tumor types. There was overlap between the anatomical locations of all tumors types with the exception of the cecum where all eight tumors identified were GISTs. Besides location, there were no unique ultrasound features of GISTs that would allow distinction from other gastrointestinal spindle cell tumors. Similar to previous studies, GISTs appeared to be the most common spindle cell tumor associated with the cecum in our sample of dogs. The high frequency of abdominal effusion with GIST's was of unknown etiology could possibly have been due to septic peritonitis.<\/jats:p>","DOI":"10.1111\/vru.12253","type":"journal-article","created":{"date-parts":[[2015,4,2]],"date-time":"2015-04-02T19:59:55Z","timestamp":1428004795000},"page":"432-438","source":"Crossref","is-referenced-by-count":20,"title":["ULTRASONOGRAPHIC FEATURES OF CANINE GASTROINTESTINAL STROMAL TUMORS COMPARED TO OTHER GASTROINTESTINAL SPINDLE CELL TUMORS"],"prefix":"10.1111","volume":"56","author":[{"given":"Joshua","family":"Hobbs","sequence":"first","affiliation":[{"name":"Tufts Cummings School of Veterinary Medicine North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Sutherland\u2010Smith","sequence":"additional","affiliation":[{"name":"Tufts Cummings School of Veterinary Medicine North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Penninck","sequence":"additional","affiliation":[{"name":"Tufts Cummings School of Veterinary Medicine North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Jennings","sequence":"additional","affiliation":[{"name":"Tufts Cummings School of Veterinary Medicine North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Barber","sequence":"additional","affiliation":[{"name":"Tufts Cummings School of Veterinary Medicine North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce","family":"Barton","sequence":"additional","affiliation":[{"name":"University of Massachusetts Worcester MA 01655"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"335","volume-title":"Small animal clinical oncology","author":"Phillips BS","year":"2001"},{"key":"e_1_2_5_3_1","first-page":"281","article-title":"Intestinal leiomyosarcoma in six dogs","volume":"24","author":"Bruecker KA","year":"1988","journal-title":"J Am Anim Hosp Assoc"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2003.tb01331.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.2460\/javma.1992.201.07.1077","article-title":"Leiomyosarcoma in dogs: 44 cases (1983\u20131988)","volume":"201","author":"Kapatkin AS","year":"1992","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1994.tb02059.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.40-1-42"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.2007.00271.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.230.9.1329"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098589703400406"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2262011880"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v10.i16.2417"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2009.28.7.941"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1994.tb02045.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2009.01516.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21909"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603797"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvru.12253","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvru.12253","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.12253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T04:51:38Z","timestamp":1717822298000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.12253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1111\/vru.12253"],"URL":"https:\/\/doi.org\/10.1111\/vru.12253","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}