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The purpose of this cross\u2010sectional retrospective study was to describe magnetic resonance imaging (MRI) features and outcome for a group of dogs and cats with solitary CNS<jats:italic>Coccidiodes<\/jats:italic>granulomas. Nine canine and two feline cases met inclusion criteria; four diagnosed and treated with surgery and fluconazole and seven diagnosed by serology or cytology and treated medically. Three cases had left<jats:italic>Coccidioides<\/jats:italic>endemic areas long before developing neurological disease. The MRI lesions shared many features with neoplastic masses. The extra\u2010axial granulomas often had a lack of a distinct border between the mass and neural parenchyma. Four cases were extra\u2010axial and seven were intra\u2010axial, but distinguishing between extra\u2010axial and intra\u2010axial locations was sometimes challenging. The surgical cases had good outcomes and histology allowed definitive diagnosis. Medically managed patients also had generally good outcomes, with resolution of clinical signs in most cases. Findings indicated that distinction between neoplasia and focal<jats:italic>Coccidioides<\/jats:italic>granulomas based on MRI features is likely to be imprecise. Demonstration of the organism by cytology or histology is required for definitive diagnosis. The role of surgery for improving the outcome of brain or spinal coccidioidomycosis granulomas warrants further study.<\/jats:p>","DOI":"10.1111\/vru.12258","type":"journal-article","created":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T11:05:01Z","timestamp":1428404701000},"page":"520-530","source":"Crossref","is-referenced-by-count":28,"title":["MAGNETIC RESONANCE IMAGING FEATURES AND OUTCOME FOR SOLITARY CENTRAL NERVOUS SYSTEM<i>COCCIDIOIDES<\/i>GRANULOMAS IN 11 DOGS AND CATS"],"prefix":"10.1111","volume":"56","author":[{"given":"R. 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