{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T16:29:59Z","timestamp":1749486599655},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,8,4]],"date-time":"2015-08-04T00:00:00Z","timestamp":1438646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:p>Potential benefits of planning radiation therapy on a contrast\u2010enhanced computed tomography scan (ceCT) should be weighed against the possibility that this practice may be associated with an inadvertent risk of overdosing nearby normal tissues. This study investigated the influence of ceCT on intensity\u2010modulated stereotactic body radiotherapy (IM\u2010SBRT) planning. Dogs with head and neck, pelvic, or appendicular tumors were included in this retrospective cross\u2010sectional study. All IM\u2010SBRT plans were constructed on a pre\u2010 or ceCT. Contours for tumor and organs at risk (OAR) were manually constructed and copied onto both CT's; IM\u2010SBRT plans were calculated on each CT in a manner that resulted in equal radiation fluence. The maximum and mean doses for OAR, and minimum, maximum, and mean doses for targets were compared. Data were collected from 40 dogs per anatomic site (head and neck, pelvis, and limbs). The average dose difference between minimum, maximum, and mean doses as calculated on pre\u2010 and ceCT plans for the gross tumor volume was less than 1% for all anatomic sites. Similarly, the differences between mean and maximum doses for OAR were less than 1%. The difference in dose distribution between plans made on CTs with and without contrast enhancement was tolerable at all treatment sites. Therefore, although caution would be recommended when planning IM\u2010SBRT for tumors near \u201creservoirs\u201d for contrast media (such as the heart and urinary bladder), findings supported the use of ceCT with this dose calculation algorithm for both target delineation and IM\u2010SBRT treatment planning.<\/jats:p>","DOI":"10.1111\/vru.12281","type":"journal-article","created":{"date-parts":[[2015,8,5]],"date-time":"2015-08-05T03:12:57Z","timestamp":1438744377000},"page":"687-695","source":"Crossref","is-referenced-by-count":12,"title":["DOSIMETRIC CONSEQUENCES OF USING CONTRAST\u2010ENHANCED COMPUTED TOMOGRAPHIC IMAGES FOR INTENSITY\u2010MODULATED STEREOTACTIC BODY RADIOTHERAPY PLANNING"],"prefix":"10.1111","volume":"56","author":[{"given":"Hiroto","family":"Yoshikawa","sequence":"first","affiliation":[{"name":"Department of Environmental and Radiologic Health Sciences Colorado State University, Fort Collins  CO 80523"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald M.","family":"Roback","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Rex Cancer Center  Raleigh NC 27607"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan M.","family":"Larue","sequence":"additional","affiliation":[{"name":"Department of Environmental and Radiologic Health Sciences Colorado State University, Fort Collins  CO 80523"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael W.","family":"Nolan","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Center for Comparative Medicine and Translational Research, North Carolina State University  Raleigh NC 27695"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,8,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.coc.0000170796.89560.02"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meddos.2011.01.007"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2014.02.040"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v12i1.3348"},{"key":"e_1_2_5_6_1","volume-title":"The physics of radiation therapy,","author":"Khan FM.","year":"2010"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-9485.2009.02046.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2012.06.046"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/46\/10\/308"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2009.01522.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2011.01838.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2012.00946.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/COC.0b013e3181a44637","article-title":"The effect of intravenous contrast on photon radiation therapy dose calculations for lung cancer","volume":"33","author":"Shi WS","year":"2010","journal-title":"Am J Clin Oncol"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2007.05.015"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmp.2012.08.002"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2006.09.010"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-717X-8-244"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1980.tb01658.x"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvru.12281","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.12281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:23:30Z","timestamp":1696033410000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.12281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,4]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1111\/vru.12281"],"URL":"https:\/\/doi.org\/10.1111\/vru.12281","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,4]]}}}