{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:03:58Z","timestamp":1787504638675,"version":"build-2736575974"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,15]],"date-time":"2016-12-15T00:00:00Z","timestamp":1481760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p>\n                    Progressive myelomalacia is an uncommon type of ischemic, hemorrhagic spinal cord infarction. Diagnosis can be difficult, but prompt recognition is important. We hypothesized that cerebrospinal fluid signal attenuation on magnetic resonance (MR) images would be more extensive in dogs that developed progressive myelomalacia vs. control dogs. A retrospective analytic cohort study was designed. Dogs were included if they presented for acute paraplegia and loss of deep pain perception and had undergone MR imaging using both sagittal single\u2010shot turbo spin echo (SSTSE) and standard sagittal T2\u2010weighted fast spin echo (T2W) pulse sequences. Dogs were divided into progressive myelomalacia and control groups for comparisons. All MR examinations were evaluated by three reviewers blinded to patient outcome. Length of cerebrospinal fluid attenuation was recorded as a ratio to the length of the L2 vertebral body in SSTSE and T2W sequences (CSF:L2\n                    <jats:sub>SSTSE<\/jats:sub>\n                    and CSF:L2\n                    <jats:sub>T2<\/jats:sub>\n                    , respectively). Length of intramedullary spinal cord hyperintensity was recorded as a ratio to the length of the L2 vertebral body in T2W sequences. A total of 21 dogs were included (five in the progressive myelomalacia group and 16 in the control group). The mean CSF:L2\n                    <jats:sub>SSTSE<\/jats:sub>\n                    attenuation value was significantly higher in dogs that developed progressive myelomalacia (CSF:L2\n                    <jats:sub>SSTSE<\/jats:sub>\n                    = 10.7) compared to controls (CSF:L2\n                    <jats:sub>SSTSE<\/jats:sub>\n                    = 5.4;\n                    <jats:italic>P<\/jats:italic>\n                    = 0.015). A cut off ratio of attenuation &gt;7.4 provided optimal differentiation between groups in this study. Findings supported the conclusion that dogs with CSF:L2\n                    <jats:sub>SSTSE<\/jats:sub>\n                    \u2264 7.4 are unlikely to develop progressive myelomalacia while dogs with CSF:L2\n                    <jats:sub>SSTSE<\/jats:sub>\n                    &gt; 7.4 are indeterminate for progressive myelomalacia.\n                  <\/jats:p>","DOI":"10.1111\/vru.12463","type":"journal-article","created":{"date-parts":[[2016,12,17]],"date-time":"2016-12-17T05:21:11Z","timestamp":1481952071000},"page":"197-205","source":"Crossref","is-referenced-by-count":29,"title":["SINGLE\u2010SHOT TURBO SPIN ECHO PULSE SEQUENCE FINDINGS IN DOGS WITH AND WITHOUT PROGRESSIVE MYELOMALACIA"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5521-8301","authenticated-orcid":false,"given":"Lindsey J.","family":"Gilmour","sequence":"first","affiliation":[{"name":"Veterinary Clinical Sciences Department, College of Veterinary Medicine Iowa State University  1600 South 16th Street Ames IA 50011"},{"name":"Veterinary Large Animal Clinical Sciences, College of Veterinary Medicine Texas A&amp;M University  4475 TAMU College Station TX 77845\u20104475"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick D.","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Sciences Department, College of Veterinary Medicine Iowa State University  1600 South 16th Street Ames IA 50011"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Miles","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Sciences Department, College of Veterinary Medicine Iowa State University  1600 South 16th Street Ames IA 50011"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Riedesel","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Sciences Department, College of Veterinary Medicine Iowa State University  1600 South 16th Street Ames IA 50011"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1972.tb06870.x"},{"key":"e_1_2_6_3_1","first-page":"256","article-title":"Loss of deep pain sensation following thoracolumbar intervertebral disk herniation in dogs: pathophysiology","volume":"25","author":"Amsellem PM","year":"2003","journal-title":"Compend Contin Edu Pract Vet"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2015.04.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2005.00109.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-736X2013000200014"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.237.10.1160"},{"key":"e_1_2_6_8_1","volume-title":"Veterinary neuroanatomy and clinical neurology,","author":"DeLahunta A","year":"2009"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.248.4.386"},{"key":"e_1_2_6_10_1","first-page":"374","volume-title":"Veterinary surgery: small animal","author":"Olby NJ","year":"2012"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semss.2007.09.009"},{"key":"e_1_2_6_12_1","first-page":"959","article-title":"MR imaging of acute spinal cord injury: results of an experimental study in dogs","volume":"11","author":"Shouman\u2010Claeys E","year":"1990","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.227.1454"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2006.00136.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2014.244"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvru.12463","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.12463","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T10:26:03Z","timestamp":1696155963000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.12463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,15]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/vru.12463"],"URL":"https:\/\/doi.org\/10.1111\/vru.12463","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,15]]}}}