{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:02:49Z","timestamp":1791302569022,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,2,23]],"date-time":"2017-02-23T00:00:00Z","timestamp":1487808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002661","name":"Fonds De La Recherche Scientifique - FNRS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p>Canine idiopathic pulmonary fibrosis is a progressive interstitial lung disease mainly affecting West Highland white terriers. Thoracic high\u2010resolution computed tomographic (T\u2010HRCT) findings for Canine idiopathic pulmonary fibrosis acquired under general anesthesia have been described previously. However, the use of general anesthesia may be contraindicated for some affected dogs. Sedation may allow improved speed and safety, but it is unknown whether sedation would yield similar results in identification and grading of Canine idiopathic pulmonary fibrosis lesions. The aim of this prospective, observational, method\u2010comparison, case\u2010control study was to compare findings from T\u2010HRCT images acquired under sedation versus general anesthesia for West Highland white terriers affected with Canine idiopathic pulmonary fibrosis (<jats:italic>n<\/jats:italic> = 11) and age\u2010matched controls (<jats:italic>n<\/jats:italic> = 9), using the glossary of terms of the Fleischner Society and a scoring system. Ground\u2010glass opacity was identified in all affected West Highland white terriers for both sedation and general anesthesia acquisitions, although the Ground\u2010glass opacity extent varied significantly between the two acquisitions (<jats:italic>P<\/jats:italic>\u00a0&lt; 0.001). Ground\u2010glass opacity was the sole lesion observed in control dogs (<jats:italic>n<\/jats:italic> = 6), but was less extensive compared with affected West Highland white terriers. Identification and grading of a mosaic attenuation pattern differed significantly between acquisitions (<jats:italic>P<\/jats:italic> &lt; 0.001). Identification of lesions such as consolidations, nodules, parenchymal and subpleural bands, bronchial wall thickening, and bronchiectasis did not differ between acquisitions. The present study demonstrated that T\u2010HRCT obtained under sedation may provide different information than T\u2010HRCT obtained under general anesthesia for identification and grading of some Canine idiopathic pulmonary fibrosis lesions, but not all of them. These differences should be taken into consideration when general anesthesia is contraindicated and sedation is necessary for evaluating West Highland white terriers with Canine idiopathic pulmonary fibrosis.<\/jats:p>","DOI":"10.1111\/vru.12481","type":"journal-article","created":{"date-parts":[[2017,2,23]],"date-time":"2017-02-23T05:56:38Z","timestamp":1487829398000},"page":"284-294","source":"Crossref","is-referenced-by-count":22,"title":["COMPARISON BETWEEN SEDATION AND GENERAL ANESTHESIA FOR HIGH RESOLUTION COMPUTED TOMOGRAPHIC CHARACTERIZATION OF CANINE IDIOPATHIC PULMONARY FIBROSIS IN WEST HIGHLAND WHITE TERRIERS"],"prefix":"10.1111","volume":"58","author":[{"given":"Elodie","family":"Roels","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Fundamental and Applied Research for Animals &amp; Health (FARAH), University of Li\u00e8ge  4000 Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Couvreur","sequence":"additional","affiliation":[{"name":"Department of Radiology Christian Hospital Center Li\u00e8ge  Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Farnir","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics applied to Veterinary Sciences, Faculty of Veterinary Medicine Fundamental and Applied Research for Animals &amp; Health (FARAH), University of Li\u00e8ge  4000 Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Clercx","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Fundamental and Applied Research for Animals &amp; Health (FARAH), University of Li\u00e8ge  4000 Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johny","family":"Verschakelen","sequence":"additional","affiliation":[{"name":"Department of Radiology Faculty of Medicine University Clinic Leuven  3000 Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e9raldine","family":"Bolen","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Fundamental and Applied Research for Animals &amp; Health (FARAH), University of Li\u00e8ge  4000 Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2013.08.003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2011.0694.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.144.22.611"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2013.03.006"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-37-2-119"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.42-1-35"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2005.tb00334.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.c6519"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2462070712"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2010.03.011"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12281"},{"key":"e_1_2_8_13_1","first-page":"263","volume-title":"Small animal internal medicine","author":"Nelson RW","year":"2014"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12531"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpradiol.2014.01.004"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2015140308"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.7067"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.70.8.986"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.68.9.925"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2010.01776.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12187"}],"container-title":["Veterinary Radiology &amp; 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