{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T11:28:59Z","timestamp":1777548539392,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,9]],"date-time":"2017-10-09T00:00:00Z","timestamp":1507507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In humans, a CT \u201ctree\u2010in\u2010bud\u201d pattern has been described as a characteristic of centrilobular bronchiolar dilation, with bronchiolar plugging by mucus, pus, or fluid. Aims of this retrospective, descriptive, multi\u2010center study were to characterize the CT appearance of a \u201ctree\u2010in\u2010bud\u201d pattern in a group of cats, and compare this pattern with radiographic and clinical findings. Databases from four hospitals were searched during the period of\u00a0January 2012 to September 2015 and cats with thoracic radiographs, thoracic CT scans and CT reports describing findings consistent with a \u201ctree\u2010in\u2010bud\u201d pattern were included. Images were reviewed by two veterinary radiologists and characteristics were recorded based on consensus. Clinical findings were recorded by one observer from each center. Thirty\u2010six cats met inclusion criteria. Six cats were asymptomatic, 12 were diagnosed with bronchial disease and 23 were suspected to have bronchial disease. Right cranial and right caudal lung lobes were most commonly affected on both imaging modalities. Localization of the \u201ctree\u2010in\u2010bud\u201d pattern was most often peripheral. On radiographs, the CT \u201ctree\u2010in\u2010bud\u201d pattern often appeared as soft\u2010tissue opacity nodules; their number and affected pulmonary segments were often underestimated compared with CT. In conclusion, the \u201ctree\u2010in\u2010bud\u201d pattern should be considered as a differential diagnosis for radiographic soft tissue opaque nodules in feline lungs. Based on lesion localization and presence or suspicion of a concomitant bronchial disease for cats in this sample, authors propose that the CT \u201ctree\u2010in\u2010bud\u201d pattern described in humans is also a characteristic of bronchial or bronchiolar plugging and bronchial disease in cats.<\/jats:p>","DOI":"10.1111\/vru.12564","type":"journal-article","created":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T01:38:39Z","timestamp":1507599519000},"page":"32-42","source":"Crossref","is-referenced-by-count":11,"title":["The computed tomographic \u201ctree\u2010in\u2010bud\u201d pattern: Characterization and comparison with radiographic and clinical findings in 36 cats"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9905-832X","authenticated-orcid":false,"given":"Harriet","family":"Hahn","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging, Universit\u00e9 Paris\u2010Est Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort Maisons\u2010Alfort France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swan","family":"Specchi","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Veterinary Institute of Novara Strada Provinciale 9, 28060, Granozzo con Monticello (NO) Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Masseau","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Facult\u00e9 de M\u00e9decine V\u00e9t\u00e9rinaire Universit\u00e9 de Montr\u00e9al Saint\u2010Hyacinthe QC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"Reinero","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine and Surgery and Comparative Internal Medicine Laboratory, College of Veterinary Medicine University of Missouri Columbia MO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghita","family":"Benchekroun","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Universit\u00e9 Paris\u2010Est Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort Maisons\u2010Alfort France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime","family":"Rechy","sequence":"additional","affiliation":[{"name":"Department of Molecular Biomedical Sciences North Carolina State University Raleigh NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Seiler","sequence":"additional","affiliation":[{"name":"Department of Molecular Biomedical Sciences North Carolina State University Raleigh NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascaline","family":"Pey","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Universit\u00e9 Paris\u2010Est Ecole Nationale V\u00e9t\u00e9rinaire d'Alfort 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