{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:21:10Z","timestamp":1787016070296,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T00:00:00Z","timestamp":1543190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006928","name":"The Ohio State University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006928","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Wexner Medical Center"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Pulmonary valve stenosis (PS) is one of the most commonly diagnosed congenital heart defects in dogs. Currently, transthoracic echocardiography (TTE) is the standard modality used to evaluate PS. Image acquisition by TTE can be challenging in some brachycephalic breeds of dogs. The use of echocardiographic\u2010gated CT angiography (ECG\u2010gated CTA) in veterinary medicine is limited. This retrospective method comparison study investigated right and left ventricular outflow diameters by sedated ECG\u2010gated CTA and unsedated TTE in 14 brachycephalic dogs with PS and 12 brachycephalic dogs without PS. Measurements of ventricular outflow structures were made in early systole and end diastole for both modalities and then compared for significance between systolic and diastolic phases, as well as between the two modalities. Ratios of the pulmonary trunk diameter to the aorta at different locations (aortic valve, aortic annulus, and ascending aorta) and in different planes (transverse, sagittal) were compared between dogs with PS and without PS, as well as within dogs, by both TTE and ECG\u2010gated CTA. Transthoracic echocardiography and ECG\u2010gated CTA both detected significantly greater pulmonary trunk to aorta ratios in dogs with PS at all aortic locations (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Pulmonary valve to aortic valve ratios were significantly smaller in dogs with PS (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Pulmonary trunk to aorta and pulmonary valve to aorta ratios were achieved with good anatomic detail using ECG\u2010gated CTA. Ratios of the pulmonary trunk and pulmonary valve relative to the aorta may be useful to evaluate for PS using a modality that is underutilized for cardiac assessment.\n                  <\/jats:p>","DOI":"10.1111\/vru.12701","type":"journal-article","created":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T11:00:09Z","timestamp":1543230009000},"page":"145-158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Electrocardiography\u2010gated cardiac CT angiography can differentiate brachycephalic dogs with and without pulmonary valve stenosis and findings differ from transthoracic echocardiography"],"prefix":"10.1111","volume":"60","author":[{"given":"Ada","family":"To","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7651-4775","authenticated-orcid":false,"given":"Eric T.","family":"Hostnik","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaylyn D.","family":"Rhinehart","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine The Ohio State University Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7427-2402","authenticated-orcid":false,"given":"Brian A.","family":"Scansen","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine The Ohio State University Columbus Ohio"},{"name":"Department of Clinical Sciences, College of Veterinary Medicine Colorado State University Fort Collins Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2015.06.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2011.0711.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118910924.ch59"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(81)90548-8"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2001.tb01590.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ctsap.2005.05.003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2012.01976.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12234"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03625.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.174.3.2305059"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/02841850600977760"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12540"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12363"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2017.10.003"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-014-0242-3"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2011.01826.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12185"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12149"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.74.7.990"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.73.3.393"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.77.11.1211"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2001.tb01239.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2009.0458.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.2460\/javma.1990.196.01.115","article-title":"Pulmonic stenosis caused by single coronary artery in dogs: Four cases (1965\u20101984)","volume":"196","author":"Buchanan JW","year":"1990","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/vaa.12110"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1984.tb01910.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4825(89)90036-X"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/RTI.0b013e31819f9369"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2011.06.053"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.102724"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2015.09.003"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2015.08.008"},{"key":"e_1_2_7_35_1","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/S0022-3565(25)10402-3","article-title":"Hemodynamic and sedative effects of dexmedetomidine in dog","volume":"263","author":"Bloor BC","year":"1992","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_2_7_36_1","first-page":"530","article-title":"Effects of sedation with dexmedetomidine and buprenorphine on echocardiographic variables, blood pressure and heart rate in healthy cats","volume":"17","author":"Johard E","year":"2017","journal-title":"J Feline Med Surg"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12346"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14814"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X14551187"},{"key":"e_1_2_7_40_1","first-page":"60","volume-title":"The Essential Physics of Medical Imaging","author":"Bushberg JT","year":"2012"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvru.12701","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.12701","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T05:59:59Z","timestamp":1775282399000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.12701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,26]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/vru.12701"],"URL":"https:\/\/doi.org\/10.1111\/vru.12701","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,26]]},"assertion":[{"value":"2018-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}