{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:20:40Z","timestamp":1787016040739,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,27]],"date-time":"2020-12-27T00:00:00Z","timestamp":1609027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Ultrasonography is increasingly being used as a clinical and research method for evaluating the gastrointestinal tract in horses, however published studies comparing ultrasonographic and histologic characteristics of equine intestinal wall layers are currently lacking. Objectives of this prospective, observational, methods comparison, case series study were to compare the layering pattern and thickness of the intestinal wall layers determined using\n                    <jats:italic>ex vivo<\/jats:italic>\n                    and\n                    <jats:italic>in vivo<\/jats:italic>\n                    ultrasonography with those determined using histology. For the\n                    <jats:italic>ex vivo<\/jats:italic>\n                    study, twelve horses were euthanized for reasons unrelated to gastrointestinal disease, and samples of the duodenum, jejunum, ileum, cecum, right dorsal colon, and small colon were collected and imaged sonographically\n                    <jats:italic>ex vivo<\/jats:italic>\n                    in an isotonic bath within 1\u00a0hour of euthanasia. For the\n                    <jats:italic>in vivo<\/jats:italic>\n                    study, ultrasonography was performed in four clinical cases, and findings were compared with histopathology. A 5\u2010layer pattern of alternating echogenicity was observed in 70 of 72\n                    <jats:italic>ex vivo<\/jats:italic>\n                    samples. Agreement between histologic and sonographic measurements was deemed good for all segments except the ileum. Formalin fixation did not alter the sonographic appearance or wall measurements. Findings from the four clinical cases illustrated the feasibility of also obtaining ultrasonographic images with sufficient sonographic detail\n                    <jats:italic>in vivo<\/jats:italic>\n                    to recognize wall layering and obtain comparable results to pathologic lesions. Findings from the current study can serve as background for future studies comparing ultrasonographic characteristics of the intestinal wall in horses with different gastrointestinal diseases.\n                  <\/jats:p>","DOI":"10.1111\/vru.12946","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T00:32:28Z","timestamp":1609115548000},"page":"316-330","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ex vivo comparison of ultrasonographic intestinal wall layering with histology in horses: A feasibilty study"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5583-2328","authenticated-orcid":false,"given":"Kari E.","family":"Bevevino","sequence":"first","affiliation":[{"name":"Department of Large Animal Clinical Sciences College of Veterinary Medicine &amp; Biomedical Sciences, Texas A&amp;M University College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology College of Veterinary Medicine &amp; Biomedical Sciences, Texas A&amp;M University College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noah D.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences College of Veterinary Medicine &amp; Biomedical Sciences, Texas A&amp;M University College Station Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristobal Navas","family":"de Solis","sequence":"additional","affiliation":[{"name":"Department of Clinical Studies New Bolton Center, University of Pennsylvania Kennett Square Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,27]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"United States Department of Agriculture APHIS.Baseline reference of equine health and management in the United States 2015. 2020.https:\/\/www.aphis.usda.gov\/aphis\/ourfocus\/animalhealth\/monitoring-and-surveillance\/nahms\/nahms_equine_studies. Accessed June 2 2020."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2014.04.011"},{"key":"e_1_2_9_4_1","first-page":"273","volume-title":"Adult Abdominal Ultrasonography in Equine Diagnostic Ultrasound","author":"Reef V","year":"1998"},{"issue":"9","key":"e_1_2_9_5_1","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.2460\/javma.1996.209.09.1597","article-title":"Use of diagnostic ultrasonography in horses with signs of acute abdominal pain","volume":"209","author":"Klohnen A","year":"1996","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2011.00428.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2006.tb00762.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.232.9.1345"},{"key":"e_1_2_9_9_1","unstructured":"WhitcombMB.Ultrasound in equine practice\u2014where we've been where we are now and where we need to go. Paper presented at:Proceedings of the 60th AAEP Annual Convention; December 6\u201010 2014;Salt Lake City UT."},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2011.01.002"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2007.00302.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12133"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.148.26.812"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2008.00369.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2011.00478.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2004.04038.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.253.1.108"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1992.tb02858.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.222.1248"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2015.11.003"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12392"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1586\/erd.12.6"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2018.05.001"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-004-2358-5"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12413"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2010.01715.x"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2008.00367.x"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0186825"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/inpract.24.4.204"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2008.00426.x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/75.4.800"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2007.00318.x"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2003.tb00509.x"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15471"}],"updated-by":[{"DOI":"10.1111\/vru.12950","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,1,24]],"date-time":"2021-01-24T00:00:00Z","timestamp":1611446400000}}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.12946","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vru.12946","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.12946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T02:08:28Z","timestamp":1724119708000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.12946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,27]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/vru.12946"],"URL":"https:\/\/doi.org\/10.1111\/vru.12946","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,27]]},"assertion":[{"value":"2020-02-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}