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The aim of this prospective, anatomical and reference interval study was to establish quantitative radiographic reference range measurements for the vertebral heart score (VHS) in rats. Right lateral (RL), ventrodorsal (VD), and dorsoventral (DV) radiographs of clinically healthy rats (<jats:italic>n<\/jats:italic>\u00a0=\u00a0124) were evaluated. Measurements were performed by 2 expert readers who were unaware of signalment data. The mean values and references intervals of VHS were 7.7 and 7.0\u20138.5 for the RL, 7.5 and 6.6\u20138.6 for the VD, and 7.9 and 6.9\u20139.0 for the DV, with VHS values greater in males than in females. The measurements reported in this study can be used by the clinician as an objective tool to evaluate cardiac size in rats, in order to improve the diagnosis and treatment of cardiac diseases.<\/jats:p>","DOI":"10.1111\/vru.12973","type":"journal-article","created":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T03:23:36Z","timestamp":1617679416000},"page":"394-401","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Vertebral heart score to evaluate cardiac size in thoracic radiographs of 124 healthy rats (<i>Rattus norvegicus<\/i>)"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2656-8345","authenticated-orcid":false,"given":"Sara","family":"Dias","sequence":"first","affiliation":[{"name":"Hospital Cl\u00ednic Veterinari \u2013 UAB, Bellaterra, Barcelona, Spain"},{"name":"Present address: Sara Dias, Pride Veterinary Centre \u2010 Referral Hospital and Nottingham University 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