{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T10:23:50Z","timestamp":1748255030946},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Subungual keratoacanthoma (SKA) is a rare benign nail bed tumor in dogs, and its radiographic characteristics have not been reported based on the authors\u2019 review of the literature. The purpose of this multicenter, retrospective, observational, descriptive study was to describe the radiographic features of SKA in dogs. Twelve dogs for a total of 12 digits with histologically confirmed SKA met the inclusion criteria. The radiographs of the manus or pes were reviewed by two veterinary radiologists and one veterinarian. The\u00a0radiology\u00a0reports were interpreted based on a consensus. In six dogs, there was lysis of both the middle phalanx (P2) and the distal phalanx (P3), whereas in the other six dogs, there was only lysis of P3. In all dogs with osteolysis of P2, the lysis involved the distal articular surface. Osteolysis of P3 was more severe in the ungual process than in the ungual crest in all dogs. The margins of the lytic regions of P2 and P3 were well defined and smoothly marginated in most dogs. Expansile changes in the P3 crest were observed in 83.3% (10\/12 dogs), and the nail of the affected digit was enlarged and deformed in 91.6% (11\/12 dogs). In summary, the radiographic features of canine SKA include severe pressure resorption of the P3 ungual process, expansile change of the P3 ungual crest, and nail enlargement and deformation. With these radiographic features, SKA should be considered as a differential diagnosis.<\/jats:p>","DOI":"10.1111\/vru.13083","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T07:29:54Z","timestamp":1648538994000},"page":"513-517","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Radiographic characteristics of canine subungual keratoacanthoma"],"prefix":"10.1111","volume":"63","author":[{"given":"Atsushi","family":"Toshima","sequence":"first","affiliation":[{"name":"Japan Small Animal Medical Center Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline V.","family":"Fulkerson","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine Purdue University Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garret S.","family":"Oetelaar","sequence":"additional","affiliation":[{"name":"VCA Canada CARE Centre Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumiko","family":"Kagawa","sequence":"additional","affiliation":[{"name":"North Lab, Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Aoki","sequence":"additional","affiliation":[{"name":"Pet clinic Aoki Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masami","family":"Higuchi","sequence":"additional","affiliation":[{"name":"Tochinokidobutsu Clinic Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kotomi","family":"Sawa","sequence":"additional","affiliation":[{"name":"Hyogo Pet Medical Center Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yozo","family":"Kawamura","sequence":"additional","affiliation":[{"name":"Mitsuba Animal Hospital Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaji","family":"Seino","sequence":"additional","affiliation":[{"name":"Kaji Animal Hospital Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Suruga Animal Hospital Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shogo","family":"Otaki","sequence":"additional","affiliation":[{"name":"Midori no Mori Animal Hospital Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine Purdue University Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"volume-title":"Skin diseases of the dog and cat: Clinical and histopathologic diagnosis","year":"2008","author":"Gross TL","key":"e_1_2_9_2_1"},{"volume-title":"Withrow and MacEwen's Small animal clinical oncology\u2010E\u2010book","year":"2019","author":"Vail DM","key":"e_1_2_9_3_1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.44-3-355"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.242.9.1249"},{"key":"e_1_2_9_6_1","first-page":"1181","article-title":"Canine nail bed keratoacanthoma diagnosed by immunohistochemical analysis","volume":"56","author":"Yoo CB","year":"2015","journal-title":"Can Vet J"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1996.tb01237.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"crossref","first-page":"726","DOI":"10.2460\/javma.1995.207.06.0726","article-title":"Evaluation of dogs with digit masses: 117 cases (1981\u20101991)","volume":"207","author":"Marino DJ","year":"1995","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.17555\/jvc.2017.02.34.1.61"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2005.tb02751.x"},{"volume-title":"Miller's anatomy of the dog","year":"2013","author":"Evans HE","key":"e_1_2_9_11_1"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(99)50132-0"},{"key":"e_1_2_9_13_1","first-page":"129","article-title":"Epithelial and melanocytic tumors of the skin","volume":"5","author":"Goldschmidt MH","year":"2016","journal-title":"Tumors in Domestic Animals"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00355351"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197001)25:1<141::AID-CNCR2820250121>3.0.CO;2-H"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/75.3.425"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.249.10.1135"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-48247-9.00048-6"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13083","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vru.13083","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T05:15:05Z","timestamp":1726895705000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.13083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,29]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/vru.13083"],"URL":"https:\/\/doi.org\/10.1111\/vru.13083","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"type":"print","value":"1058-8183"},{"type":"electronic","value":"1740-8261"}],"subject":[],"published":{"date-parts":[[2022,3,29]]},"assertion":[{"value":"2021-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}