{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:21:32Z","timestamp":1787016092694,"version":"build-2736575974"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Subungual keratoacanthoma (SK) is a digital neoplasm that has rarely been reported in dogs and carries an excellent prognosis following surgical removal. Radiographic features of canine SK have only been briefly discussed in two prior case reports. Both articles described extensive distal phalangeal osteolysis, a feature more commonly associated with malignant digital neoplasms (e.g., subungual squamous cell carcinoma (SCC) or melanoma). This retrospective case series aimed to further characterize radiographic findings of histologically confirmed canine SK. Seven dogs met the inclusion criteria, with a total of seven affected digits. All seven digits (100%) had osteolysis of the distal phalanx's ungual process and crest, as well as regional soft tissue swelling. Osteolysis of the ungual process was severe in all cases, with complete destruction in six of seven digits (86%). Partial ungual crest geographic and expansile osteolysis was noted in four of seven digits (57%), while two digits (28%) had complete ungual crest destruction. Seven of seven digits (100%) had a radiographically thickened claw, and two of seven digits (28%) had associated lysis of the distal aspect of the middle phalanx. Based on these findings, an osteolytic subungual mass should not be considered pathognomonic for malignant neoplasia. Observing the imaging features previously described should prompt veterinarians to consider SK as a differential diagnosis.<\/jats:p>","DOI":"10.1111\/vru.13108","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T13:52:20Z","timestamp":1652709140000},"page":"675-680","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Radiographic features of subungual keratoacanthomas in dogs"],"prefix":"10.1111","volume":"63","author":[{"given":"Chelsea J.","family":"O'Toole","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging Schwarzman Animal Medical Center  New York NY 10065 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taryn A.","family":"Donovan","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Schwarzman Animal Medical Center  New York NY 10065 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0547-4945","authenticated-orcid":false,"given":"Alexandre B.","family":"Le Roux","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging Schwarzman Animal Medical Center  New York NY 10065 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.44-3-355"},{"key":"e_1_2_9_3_1","first-page":"88","volume-title":"Tumors in Domestic Animals","author":"Goldschmidt MH","year":"2017"},{"key":"e_1_2_9_4_1","first-page":"1181","article-title":"Canine nail bed keratoacanthoma diagnosed by immunohistochemical analysis","volume":"56","author":"Yoo CB","year":"2015","journal-title":"Can Vet J"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00355351"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.244.9.1031"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1996.tb01237.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.185.1.01850174"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.645982"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985813490757"},{"key":"e_1_2_9_11_1","first-page":"121","volume-title":"Epithelial Tumors of the Skin","author":"Goldschmidt MH","year":"2018"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2005.tb02751.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1992.tb01432.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.242.9.1249"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870701900420"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13108","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vru.13108","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vru.13108","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T13:00:47Z","timestamp":1692536447000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vru.13108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,16]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/vru.13108"],"URL":"https:\/\/doi.org\/10.1111\/vru.13108","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,16]]},"assertion":[{"value":"2021-10-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}